Is enzyme immobilization a mature discipline? Some critical considerations to capitalize on the benefits of immobilization
JM Bolivar, JM Woodley… - Chemical Society …, 2022 - pubs.rsc.org
Enzyme immobilization has been developing since the 1960s and although many industrial
biocatalytic processes use the technology to improve enzyme performance, still today we …
biocatalytic processes use the technology to improve enzyme performance, still today we …
Multistep enzyme cascades as a route towards green and sustainable pharmaceutical syntheses
Enzyme cascades are a powerful technology to develop environmentally friendly and cost-
effective synthetic processes to manufacture drugs, as they couple different …
effective synthetic processes to manufacture drugs, as they couple different …
Enzymes, In Vivo Biocatalysis, and Metabolic Engineering for Enabling a Circular Economy and Sustainability
Since the industrial revolution, the rapid growth and development of global industries have
depended largely upon the utilization of coal-derived chemicals, and more recently, the …
depended largely upon the utilization of coal-derived chemicals, and more recently, the …
The rise of continuous flow biocatalysis–fundamentals, very recent developments and future perspectives
Biocatalysis community has witnessed a drastic increase in the number of studies for the use
of enzymes in continuously operated flow reactors. This significant interest arose from the …
of enzymes in continuously operated flow reactors. This significant interest arose from the …
Round, round we go–strategies for enzymatic cofactor regeneration
S Mordhorst, JN Andexer - Natural product reports, 2020 - pubs.rsc.org
Covering: up to the beginning of 2020 Enzymes depending on cofactors are essential in
many biosynthetic pathways of natural products. They are often involved in key steps …
many biosynthetic pathways of natural products. They are often involved in key steps …
Putting precision and elegance in enzyme immobilisation with bio-orthogonal chemistry
X Pei, Z Luo, L Qiao, Q Xiao, P Zhang… - Chemical Society …, 2022 - pubs.rsc.org
The covalent immobilisation of enzymes generally involves the use of highly reactive
crosslinkers, such as glutaraldehyde, to couple enzyme molecules to each other or to …
crosslinkers, such as glutaraldehyde, to couple enzyme molecules to each other or to …
Continuous flow asymmetric synthesis of chiral active pharmaceutical ingredients and their advanced intermediates
Catalytic enantioselective transformations provide well-established and direct access to
stereogenic synthons that are broadly distributed among active pharmaceutical ingredients …
stereogenic synthons that are broadly distributed among active pharmaceutical ingredients …
Artificial photosynthetic cells with biotic–abiotic hybrid energy modules for customized CO2 conversion
F Gao, G Liu, A Chen, Y Hu, H Wang, J Pan… - Nature …, 2023 - nature.com
Programmable artificial photosynthetic cell is the ultimate goal for mimicking natural
photosynthesis, offering tunable product selectivity via reductase selection toward device …
photosynthesis, offering tunable product selectivity via reductase selection toward device …
Streamlining design, engineering, and applications of enzymes for sustainable biocatalysis
RA Sheldon, D Brady - ACS Sustainable Chemistry & Engineering, 2021 - ACS Publications
In this Perspective we show how an expansion of the scope and impact of biocatalysis in
industrial organic synthesis is enabled by streamlining the underpinning biocatalyst and …
industrial organic synthesis is enabled by streamlining the underpinning biocatalyst and …
Flow biocatalysis: A challenging alternative for the synthesis of APIs and natural compounds
Biocatalysts represent an efficient, highly selective and greener alternative to metal catalysts
in both industry and academia. In the last two decades, the interest in biocatalytic …
in both industry and academia. In the last two decades, the interest in biocatalytic …