The practice of perioperative fluid therapy is variable, ranging fromhigh
volume'todry'regimen. A review of the data on the effect ofhigh volume'perioperative fluid …

Perioperative monitoring of blood coagulation is critical to better understand causes of
hemorrhage, to guide hemostatic therapies, and to predict the risk of bleeding during the …

Complex interactions exist between cytokines and the interleukin family plays a fundamental
role in inflammation. Particularly circulating IL-1β, IL-6 and IL-8 are unregulated in systemic …

Contemporary trauma care comprises advanced pre-hospital care, regionalized trauma
systems, damage control operative techniques, advanced critical care, rehabilitation with …

Severe sepsis induces coagulopathy, which may lead to disseminated intravascular
coagulation (DIC). Thromboelastometry is a point-of-care whole blood coagulation monitor …

Background: Thrombelastography (TEG®) is used to assess coagulopathy. However, a
comprehensive characterization of the effects of specific coagulation factor deficiencies and …

Complex associations exist between inflammation and thrombosis, with the inflammatory
state tending to promote coagulation. Fibrinogen, an acute phase protein, has been shown …

Alzheimer-type dementia (AD) is a neurodegenerative disorder and the most common form
of dementia. Patients typically present with neuro-and systemic inflammation and iron …

Although the two phenomena are usually studied separately, we summarise a considerable
body of literature to the effect that a great many diseases involve (or are accompanied by) …

Background In the pathogenesis of sepsis, inflammation‐induced changes in coagulation
play a pivotal role. Methods In total, 90 patients (30 patients with septic shock, 30 surgical …