MicroRNA delivery through nanoparticles

SWL Lee, C Paoletti, M Campisi, T Osaki… - Journal of Controlled …, 2019 - Elsevier
MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …

Oxidative stress and aging as risk factors for Alzheimer's disease and Parkinson's disease: the role of the antioxidant melatonin

J Tchekalarova, R Tzoneva - International journal of molecular sciences, 2023 - mdpi.com
Aging and neurodegenerative diseases share common hallmarks, including mitochondrial
dysfunction and protein aggregation. Moreover, one of the major issues of the demographic …

The role of microRNAs in neurodegenerative diseases: a review

S Li, Z Lei, T Sun - Cell Biology and Toxicology, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs which are essential post-transcriptional gene
regulators in various neuronal degenerative diseases and playact a key role in these …

miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions

SD Hsu, YT Tseng, S Shrestha, YL Lin… - Nucleic acids …, 2014 - academic.oup.com
MicroRNAs (miRNAs) are small non-coding RNA molecules capable of negatively
regulating gene expression to control many cellular mechanisms. The miRTarBase …

The epigenetics of aging and neurodegeneration

R Lardenoije, A Iatrou, G Kenis, K Kompotis… - Progress in …, 2015 - Elsevier
Epigenetics is a quickly growing field encompassing mechanisms regulating gene
expression that do not involve changes in the genotype. Epigenetics is of increasing …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

FGF receptors: cancer biology and therapeutics

M Katoh, H Nakagama - Medicinal research reviews, 2014 - Wiley Online Library
Fibroblast growth factors (FGFs) are involved in a variety of cellular processes, such as
stemness, proliferation, anti‐apoptosis, drug resistance, and angiogenesis. Here, FGF …

Non-coding RNAs in human disease

M Esteller - Nature reviews genetics, 2011 - nature.com
The relevance of the non-coding genome to human disease has mainly been studied in the
context of the widespread disruption of microRNA (miRNA) expression and function that is …

The FGF family: biology, pathophysiology and therapy

A Beenken, M Mohammadi - Nature reviews Drug discovery, 2009 - nature.com
The family of fibroblast growth factors (FGFs) regulates a plethora of developmental
processes, including brain patterning, branching morphogenesis and limb development …

microRNAs in Parkinson's disease: from pathogenesis to novel diagnostic and therapeutic approaches

L Leggio, S Vivarelli, F L'Episcopo, C Tirolo… - International journal of …, 2017 - mdpi.com
Parkinson's disease (PD) is the most prevalent central nervous system (CNS) movement
disorder and the second most common neurodegenerative disease overall. PD is …