Mathematical modeling of radiotherapy cancer treatment using Caputo fractional derivative

MF Farayola, S Shafie, FM Siam, I Khan - Computer methods and programs …, 2020 - Elsevier
Background This paper presents a mathematical model that simulates a radiotherapy cancer
treatment process. The model takes into consideration two important radiobiological factors …

Numerical simulation of normal and cancer cells' populations with fractional derivative under radiotherapy

MF Farayola, S Shafie, FM Siam, I Khan - Computer methods and programs …, 2020 - Elsevier
Background This paper presents a numerical simulation of normal and cancer cells'
population dynamics during radiotherapy. The model used for the simulation was the …

Modeling the diabetic population in Malaysia using a functional rate of unhealthy lifestyle influence

H Nasir - Journal of Statistics and Management Systems, 2021 - Taylor & Francis
Social influence poses great challenges to human behavior. The increasing prevalence of
diabetics is due to the diabetes incidence that keeps on elevated every year. In this work, we …

A time-delay model of diabetic population: Dynamics analysis, sensitivity, and optimal control

H Nasir - Physica Scripta, 2021 - iopscience.iop.org
Diabetes, also known as diabetes mellitus, is a chronic degenerative disease with a variety
of adverse complications. Due to its slow progression, a mathematical model of the diabetic …

Stability analysis and optimal control of a five-state diabetic population model

H Nasir - Journal of Statistics and Management Systems, 2022 - Taylor & Francis
There exists an extensive literature on differential equation models of diabetic population. In
this paper, we developed a five-compartmental model of diabetes population dynamics …

Elucidating the Effects of Ionizing Radiation on Immune Cell Populations: A Mathematical Modeling Approach with Special Emphasis on Fractional Derivatives

DY Alzahrani, FM Siam, FA Abdullah - Mathematics, 2023 - mdpi.com
Despite recent advances in the mathematical modeling of biological processes and real-
world situations raised in the day-to-day life phase, some phenomena such as immune cell …

Mechanistic model of radiation-induced bystander effects to cells using structured population approach

FM Siam, MH Nasir - Matematika, 2018 - matematika.utm.my
In irradiation process, instead of traverse on the targeted cells, there is side effect happens
to non-targeted cells. The targeted cells that had been irradiated with ionizing radiation …

Mathematical Models of the Generation of Radiation-induced DNA Double-strand Breaks and Misrepair Cells by Direct and Indirect Action

H Rashid, FM Siam, N Maan… - Malaysian Journal of …, 2022 - mjfas.utm.my
Free radical carries an unpaired electron in the outer shell which is very reactive and
becomes toxic to DNA. The direct action hits cell directly, while indirect action is the …

[PDF][PDF] Comparison of parameter fitting on the model of irradiation effects on bystander cells between Nelder-Mead simplex and particle swarm optimization

FM Siam, MH Nasir - Journal of Advances in Technology and …, 2019 - tafpublications.com
The mathematical modeling framework is often developed by considering the understanding
of the biological phenomenon, intuition and assumptions. There must be several parameters …

Sensitivity analysis based on the direct differential method for dynamical systems with discrete delays

H Nasir, AAM Daud - AIP Conference Proceedings, 2024 - pubs.aip.org
Mathematical models appear in many forms, such as instantaneous dynamics (ordinary
differential equations) or time-lags dynamics (delay differential equations). It is important to …