Peripheral sensory organ damage leads to compensatory cortical plasticity that is
associated with a remarkable recovery of cortical responses to sound. The precise …

Visual stimuli that deviate from the current context elicit augmented responses in the primary
visual cortex (V1). These heightened responses, known as" deviance detection," require …

Neural cell types have classically been characterized by their anatomy and
electrophysiology. More recently, single-cell transcriptomics has enabled an increasingly …

Chronic pain often leads to the development of sleep disturbances. However, the precise
neural circuit mechanisms responsible for sleep disorders in chronic pain have remained …

Diverse types of inhibitory interneurons (INs) impart computational power and flexibility to
neocortical circuits. Whereas markers for different IN types in cortical layers 2–6 (L2–L6) …

Visual processing is strongly influenced by context. Stimuli that deviate from contextual
regularities elicit augmented responses in primary visual cortex (V1). These heightened …

The plasticity of inhibitory interneurons (INs) plays an important role in the organization and
maintenance of cortical microcircuits. Given the many different IN types, there is an even …

Gangliosides are major glycans on vertebrate nerve cells, and their metabolic disruption
results in congenital disorders with marked cognitive and motor deficits. The …

Differentiating between auditory signals of various emotional significance plays a crucial
role in an individual's ability to thrive and excel in social interactions and in survival. Multiple …

In human adolescents, females often report drinking for coping reasons to avoid negative
affective states. We have shown previously that adolescent female rats with elevated levels …