Metal-free methods for the generation of benzimidazoles and 2-aminobenzimidazoles

PJ Wanjari, N Saha, G Dubey, PV Bharatam - Tetrahedron, 2023 - Elsevier
Benzimidazoles, the important scaffold of various biologically important molecules, can be
synthesized using metal catalyzed and metal-free methodologies. Recently, metal-free …

N-substitution reactions of 2-aminobenzimidazoles to access pharmacophores

II Padilla-Martínez, A Cruz… - Current Organic …, 2023 - ingentaconnect.com
Benzimidazole (BI) and its derivatives are interesting molecules in medicinal chemistry
because several of these compounds have a diversity of biological activities and some of …

Iodoaniline Dependent Formation of N‐Aroylguanidines Versus 2‐Aminoquinazolinones from Palladium(0) Catalysed Aminocarbonylation of N‐Arylguanidines

P Yadav, N Thirupathi - European Journal of Organic Chemistry, 2024 - Wiley Online Library
Abstract A family of N, N′‐diaryl‐N′′‐(pyridine‐2‐ylmethyl) guanidines (B) were
prepared in 70%–92% yields and subjected to palladium (0) catalyzed aminocarbonylation …

2-Guanidinobenzazoles as building blocks to afford biologically active derivatives

MC Rosales-Hernandez, A Cruz… - Current Organic …, 2023 - benthamdirect.com
1, 3-Benzazoles (BZs) are interesting compounds in medicinal chemistry. For instance,
compounds with the BZ nucleus exhibit diverse biological activities and some of them are …

Synthetic Procedures to Access 2-Guanidinobenzazoles of Biological Interest

MC Rosales-Hernández… - Current Organic …, 2023 - ingentaconnect.com
Benzazoles (Bz) and derivatives are interesting molecules in medicinal chemistry. Several of
these compounds display diverse biological activities; some are still used in clinical …