Isatin and its derivatives: a survey of recent syntheses, reactions, and applications

R Kakkar - MedChemComm, 2019 - pubs.rsc.org
Isatin (1H-indole-2, 3-dione) and its derivatives represent an important class of heterocyclic
compounds that can be used as precursors for drug synthesis. Since its discovery, a lot of …

Building bridges: Biocatalytic C–C-bond formation toward multifunctional products

NG Schmidt, E Eger, W Kroutil - ACS catalysis, 2016 - ACS Publications
Carbon–carbon bond formation is the key reaction for organic synthesis to construct the
carbon framework of organic molecules. The review gives a selection of biocatalytic C–C …

Synthesis and antimicrobial activity of novel 2-thiazolylimino-5-arylidene-4-thiazolidinones

P Vicini, A Geronikaki, K Anastasia, M Incerti… - Bioorganic & medicinal …, 2006 - Elsevier
New 2-thiazolylimino-5-arylidene-4-thiazolidinones (compounds 4a–j), unsubstituted or
carrying hydroxy, methoxy, nitro and chloro groups on the benzene ring, were synthesized …

Benzofuran derivatives and their anti-tubercular, anti-bacterial activities

Z Xu, S Zhao, Z Lv, L Feng, Y Wang, F Zhang… - European Journal of …, 2019 - Elsevier
Benzofuran is a fundamental structural unit in a variety of biologically active natural
products, and its derivatives display various biological properties. Some benzofuran …

A review on synthetic chalcone derivatives as tubulin polymerisation inhibitors

W Liu, M He, Y Li, Z Peng, G Wang - Journal of enzyme inhibition …, 2022 - Taylor & Francis
Microtubules play an important role in the process of cell mitosis and can form a spindle in
the mitotic prophase of the cell, which can pull chromosomes to the ends of the cell and then …

Total synthesis of natural products containing benzofuran rings

MM Heravi, V Zadsirjan, H Hamidi, PHT Amiri - RSC advances, 2017 - pubs.rsc.org
Research on natural products containing benzofuran has remarkably increased during the
past few decades. Newly isolated natural products with complex structures are being …

Benzofuran: an emerging scaffold for antimicrobial agents

A Hiremathad, MR Patil, KR Chethana, K Chand… - RSC …, 2015 - pubs.rsc.org
Resistance to antibiotics is a major global problem and there is an urgent need to develop
new therapeutic agents. Although many classes of active compounds have been …

Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation

K Liaras, A Geronikaki, J Glamočlija, A Ćirić… - Bioorganic & medicinal …, 2011 - Elsevier
As part of ongoing studies in developing new antimicrobials, we report the synthesis of a
new class of structurally novel derivatives, that incorporate two known bioactive structures a …

Molecular modeling, synthesis, antibacterial and cytotoxicity evaluation of sulfonamide derivatives of benzimidazole, indazole, benzothiazole and thiazole

F Naaz, R Srivastava, A Singh, N Singh… - Bioorganic & Medicinal …, 2018 - Elsevier
A new series of heterocyclic molecules bearing sulfonamide linkage has been synthesized
and screened for antibacterial activity. During antibacterial screening using broath dilution …

Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety

T Nasr, S Bondock, S Eid - European journal of medicinal chemistry, 2014 - Elsevier
Abstract Development of new antimicrobial agents is a good solution to overcome drug-
resistance problems. In this context, new functionalized thiophene, acrylamide …