DNA methylation profiling: an emerging paradigm for cancer diagnosis

A Papanicolau-Sengos, K Aldape - Annual Review of Pathology …, 2022 - annualreviews.org
Histomorphology has been a mainstay of cancer diagnosis in anatomic pathology for many
years. DNA methylation profiling is an additional emerging tool that will serve as an adjunct …

WHO 2022 landscape of papillary and chromophobe renal cell carcinoma

J Lobo, R Ohashi, MB Amin, DM Berney… - …, 2022 - Wiley Online Library
The 5th edition of the WHO Classification of Tumours of the Urinary and Male Genital
Systems contains relevant revisions and introduces a group of molecularly defined renal …

[HTML][HTML] Chromophobe renal cell carcinoma: current and controversial issues

H Moch, R Ohashi - Pathology, 2021 - Elsevier
It has been 35 years since Professor Thoenes and his colleagues discovered chromophobe
renal cell carcinoma (RCC). Since then, our knowledge about this tumour entity has …

A pilot radiometabolomics integration study for the characterization of renal oncocytic neoplasia

ME Klontzas, E Koltsakis, G Kalarakis, K Trpkov… - Scientific Reports, 2023 - nature.com
Differentiating benign renal oncocytic tumors and malignant renal cell carcinoma (RCC) on
imaging and histopathology is a critical problem that presents an everyday clinical …

Low-grade oncocytic tumour expands the spectrum of renal oncocytic tumours and deserves separate classification: a review of 23 cases from a single tertiary institute

M Akgul, KI Al-Obaidy, L Cheng… - Journal of Clinical …, 2022 - jcp.bmj.com
Aims Low-grade oncocytic tumour (LOT) has recently been introduced as a potential distinct
entity. Methods At the Indiana University department of pathology, primary renal epithelial …

[HTML][HTML] Do we need an updated classification of oncocytic renal tumors?: Emergence of low-grade oncocytic tumor (LOT) and eosinophilic vacuolated tumor (EVT) as …

O Hes, K Trpkov - Modern Pathology, 2022 - Elsevier
The category of “oncocytic renal tumors''includes well-recognized entities, such as renal
oncocytoma (RO) and eosinophilic variant of chromophobe renal cell carcinoma (eo …

Characterization of a distinct low-grade oncocytic renal tumor (CD117-negative and cytokeratin 7-positive) based on a tertiary oncology center experience: the new …

Q Guo, N Liu, F Wang, Y Guo, B Yang, Z Cao, Y Wang… - Virchows Archiv, 2021 - Springer
To examine the clinicopathologic and immunohistochemical features of a group of newly
defined low-grade oncocytic renal tumors (LOT) that have the “CD117 negative/cytokeratin …

Machine Learning Integrating 99mTc Sestamibi SPECT/CT and Radiomics Data Achieves Optimal Characterization of Renal Oncocytic Tumors

ME Klontzas, E Koltsakis, G Kalarakis, K Trpkov… - Cancers, 2023 - mdpi.com
Simple Summary This study focuses on the integration of 99mTc Sestamibi SPECT/CT and
radiomics analysis to characterize benign renal oncocytic neoplasia. Our research includes …

FOXI1 expression in chromophobe renal cell carcinoma and renal oncocytoma: a study of The Cancer Genome Atlas transcriptome–based outlier mining and …

K Tong, Z Hu - Virchows Archiv, 2021 - Springer
FOXI1 is a forkhead family transcription factor that plays a key role in differentiation and
functional maintenance for the renal intercalated cell (IC). The diagnostic utility of FOXI1 is …

Birt‐Hogg‐Dubé syndrome‐associated renal cell carcinoma: Histopathological features and diagnostic conundrum

M Furuya, H Hasumi, M Yao, Y Nagashima - Cancer science, 2020 - Wiley Online Library
Abstract Birt‐Hogg‐Dubé (BHD) syndrome is associated with the development of hereditary
renal cell carcinoma (RCC) and is caused by a germline mutation in the folliculin gene. Most …