Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Phototherapeutic anticancer strategies with first-row transition metal complexes: a critical review

L Gourdon, K Cariou, G Gasser - Chemical Society Reviews, 2022 - pubs.rsc.org
Photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) are therapeutic
techniques based on a photosensitizer (PS) and light. These techniques allow the spatial …

Recent advances in functional nanomaterials for light–triggered cancer therapy

S Gai, G Yang, P Yang, F He, J Lin, D Jin, B Xing - Nano today, 2018 - Elsevier
Photo–triggered therapeutic modalities for cancer have attracted enormous attention in
recent years due to the easily focused and tuned properties of irradiation light that enable …

Phthalocyanines as medicinal photosensitizers: Developments in the last five years

X Li, BD Zheng, XH Peng, SZ Li, JW Ying… - Coordination Chemistry …, 2019 - Elsevier
Owing to their high extinction coefficients, long absorption wavelengths, and modification
tunable photophysical and photochemical properties, phthalocyanines (Pcs) have been …

Zinc (II) phthalocyanines as photosensitizers for antitumor photodynamic therapy

LP Roguin, N Chiarante, MCG Vior, J Marino - The international journal of …, 2019 - Elsevier
Photodynamic therapy (PDT) is a highly specific and clinically approved method for cancer
treatment in which a nontoxic drug known as photosensitizer (PS) is administered to a …

Photodynamic Therapy for Bladder Cancers, A Focused Review

KMM Rahman, P Giram, BA Foster… - Photochemistry and …, 2023 - Wiley Online Library
Bladder cancer is the first cancer for which PDT was clinically approved in 1993.
Unfortunately, it was unsuccessful due to side effects like bladder contraction. Here, we …

Photodegradation of organic pollutants in water by immobilized porphyrins and phthalocyanines

L Fernandez, VI Esteves, A Cunha… - Journal of Porphyrins …, 2016 - World Scientific
New methods for water treatment are required as a result from an increasing awareness in
the reduction of the pollution impact in the environment. In the perspective of the photo …

Peripherally crowded cationic phthalocyanines as efficient photosensitizers for photodynamic therapy

M Halaskova, A Rahali… - ACS Medicinal …, 2021 - ACS Publications
Photodynamic therapy is a treatment modality of cancer based on the production of cytotoxic
species upon the light activation of photosensitizers. Zinc phthalocyanine photosensitizers …

Phthalocyanines and tetrapyrazinoporphyrazines with two cationic donuts: high photodynamic activity as a result of rigid spatial arrangement of peripheral substituents

B Ghazal, M Machacek, MA Shalaby… - Journal of Medicinal …, 2017 - ACS Publications
High photodynamic activity was observed for hexadeca-cationic zinc, magnesium, and metal-
free phthalocyanines (Pcs) and tetrapyrazinoporphyrazines with EC50 values as low as 5 …

Self‐assembly of porphyrin–paclitaxel conjugates into nanomedicines: enhanced cytotoxicity due to endosomal escape

X Zheng, Z Li, L Chen, Z Xie… - Chemistry–An Asian …, 2016 - Wiley Online Library
Nanomedicines assembled directly from drug molecules possess several advantages,
including precise molecular structure and high content of drugs. Herein, porphyrin …