The most dangerous aspect of cancer lies in metastatic progression. Tumor cells will
successfully form life-threatening metastases when they undergo sequential steps along a …

Human red blood cells (RBCs) are approximately 8 μm in diameter, but must repeatedly
deform through capillaries as small as 2 μm in order to deliver oxygen to all parts of the …

The mechanical phenotype of a cell is an inherent biophysical marker of its state and
function, with many applications in basic and applied biological research. Microfluidics …

The deformability of a cell is the direct result of a complex interplay between the different
constituent elements at the subcellular level, coupling a wide range of mechanical …

In life sciences, the material properties of suspended cells have attained significance close
to that of fluorescent markers but with the advantage of label-free and unbiased sample …

Viscosity is a key property of cell membranes that controls mobility of embedded proteins
and membrane remodeling. Measuring it is challenging because existing approaches …

Techniques, such as micropipette aspiration and optical tweezers, are widely used to
measure cell mechanical properties, but are generally labor-intensive and time-consuming …

Cell deformability plays an important role in cellular processes and functions, including cell
growth and differentiation, as well as cell transfer and cell cycle. Measuring deformability at …

The loss of the red blood cells (RBCs) deformability is related with many human diseases,
such as malaria, hereditary spherocytosis, sickle cell disease, or renal diseases. Hence …

AFM-based rheology methods enable the investigation of the viscoelastic properties of
cancer cells. Such properties are known to be essential for cell functions, especially for …