Beneficial effects of Chrysin on Cadmium‐induced nephrotoxicity in rats: Modulating the levels of Nrf2/HO‐1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling …

H Şimşek, N Akaras, C Gür, S Küçükler, FM Kandemir - Gene, 2023 - Elsevier
Cadmium (Cd) is a toxic heavy metal that targets the kidney directly in the body. Chrysin
(CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and …

Vitexin attenuates chronic kidney disease by inhibiting renal tubular epithelial cell ferroptosis via NRF2 activation

J Song, H Wang, J Sheng, W Zhang, J Lei, W Gan… - Molecular …, 2023 - Springer
Background Chronic kidney disease (CKD) involves a variety of pathological processes, and
ferroptosis plays a vital role in CKD progression. Targeting ferroptosis is a promising …

An overview of the ameliorative efficacy of Catharanthus roseus extract against Cd2+ toxicity: implications for human health and remediation strategies

M Hashim, H Arif, B Tabassum, S Rehman… - Frontiers in Public …, 2024 - frontiersin.org
Rapid industrialization has led to an increase in cadmium pollution, a dangerously toxic
heavy metal. Cadmium (Cd) is released into the environment through industrial processes …

Alleviative effects of pinostrobin against cadmium-induced renal toxicity in rats by reducing oxidative stress, apoptosis, inflammation, and mitochondrial dysfunction

MU Ijaz, S Shahzadi, A Hamza, R Azmat… - Frontiers in …, 2023 - frontiersin.org
Introduction Cadmium (Cd) is a highly toxic heavy metal that can be found everywhere in the
environment and can have harmful effects on both human and animal health. Pinostrobin …

Protective effect of quercetin on cadmium-induced renal apoptosis through cyt-c/caspase-9/caspase-3 signaling pathway

R Huang, L Ding, Y Ye, K Wang, W Yu, B Yan… - Frontiers in …, 2022 - frontiersin.org
Cadmium (Cd), a heavy metal, has harmful effects on animal and human health, and it can
also obviously induce cell apoptosis. Quercetin (Que) is a flavonoid compound with …

Metal pollution and potential human health risk assessment in major seafood items (fish, crustaceans, and cephalopods)

M Haseeb-ur-Rehman, AB Munshi, U Atique… - Marine Pollution …, 2023 - Elsevier
Global seafood consumers are increasingly concerned about and prefer safe, high-quality,
and hazard-free seafood products. This study investigated various Pakistani processing …

Farnesol attenuates cadmium-induced kidney injury by mitigating oxidative stress, inflammation and necroptosis and upregulating cytoglobin and PPARγ in rats

RS Alruhaimi, EHM Hassanein, AF Ahmeda, AM Atwa… - Tissue and Cell, 2024 - Elsevier
Heavy metals are environmental pollutants that can harm animals and humans even at low
concentrations. Cadmium (Cd) is known for its serious health effects on different organs and …

Attenuation of inflammation, oxidative stress and TGF-β1/Smad3 signaling and upregulation of Nrf2/HO-1 signaling mediate the protective effect of diallyl disulfide …

RS Alruhaimi, EHM Hassanein, AF Ahmeda… - Tissue and Cell, 2024 - Elsevier
Heavy metals are toxic environmental pollutants with serious health effects on humans and
animals. Cadmium (Cd) is known for its serious nephrotoxic effect and its toxicity involves …

Asperuloside attenuates cadmium-induced toxicity by inhibiting oxidative stress, inflammation, fibrosis and apoptosis in rats

Z Kong, C Liu, OJ Olatunji - Scientific Reports, 2023 - nature.com
This present study investigated the protective effects of asperuloside (ASP) against cadmium-
induced nephrocardiac toxicity. Rats were treated with 50 mg/kg of ASP for five weeks and …

Protective Effect of Catharanthus roseus Extract on Cadmium-Induced Toxicity in Albino Rats: A Putative Mechanism of Detoxification

M Hashim, H Arif, B Tabassum, A Arif, AA Rehman… - Metabolites, 2022 - mdpi.com
Globally, people are highly affected by Cadmium (Cd), the most hazardous heavy metal. It
has been implicated in various pathogeneses. Oxidative stress may be one the main …