Background Most hospitals use traditional infection prevention (IP) methods for outbreak
detection. We developed the Enhanced Detection System for Healthcare-Associated …

Background: Whole-genome sequencing (WGS) has traditionally been used in infection
prevention to confirm or refute the presence of an outbreak after it has occurred. Due to …

Hospital outbreak investigations are high-stakes epidemiology. Contacts between staff and
patients are numerous; environmental and community exposures are plentiful; and patients …

Bacterial healthcare-associated infections (HAIs) are a substantial source of global morbidity
and mortality. The estimated cost associated with HAIs ranges from 35to 45 billion in the …

Precision public health has been defined in many ways [1]. It can be viewed as an emerging
multidisciplinary field that uses genomics, big data, and machine learning/artificial …

Background Though detection of transmission clusters of methicillin-resistant
Staphylococcus aureus (MRSA) infections is a priority for infection control personnel in …

Novel species of coagulase-negative staphylococci, which could serve as reservoirs of
virulence and antimicrobial resistance factors for opportunistic pathogens from the genus …

Objectives A defining feature of MRSA is the SCC mec element. The excision and
integration of SCC mec elements are catalysed by Ccr recombinases. Currently, seven ccrA …

Background Healthcare-associated infections pose a potentially fatal threat to patients
worldwide and Staphylococcus aureus is one of the most common causes of healthcare …

Abstract Purpose of Review Whole genome sequencing is increasingly used in
epidemiologic surveillance in healthcare centers, shedding new light on the transmission of …