Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study
AA Elfiky - Life sciences, 2020 - Elsevier
Aims A new human coronavirus (HCoV), which has been designated SARS-CoV-2, began
spreading in December 2019 in Wuhan City, China causing pneumonia called COVID-19 …
spreading in December 2019 in Wuhan City, China causing pneumonia called COVID-19 …
Anti-HCV, nucleotide inhibitors, repurposing against COVID-19
AA Elfiky - Life sciences, 2020 - Elsevier
Aims A newly emerged Human Coronavirus (HCoV) is reported two months ago in Wuhan,
China (COVID-19). Until today> 2700 deaths from the 80,000 confirmed cases reported …
China (COVID-19). Until today> 2700 deaths from the 80,000 confirmed cases reported …
SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective
AA Elfiky - Journal of Biomolecular Structure and Dynamics, 2021 - Taylor & Francis
New treatment against SARS-CoV-2 now is a must. Nowadays, the world encounters a huge
health crisis by the COVID-19 viral infection. Nucleotide inhibitors gave a lot of promising …
health crisis by the COVID-19 viral infection. Nucleotide inhibitors gave a lot of promising …
Structure-based drug design of RdRp inhibitors against SARS-CoV-2
K Shehzadi, A Saba, M Yu, J Liang - Topics in Current Chemistry, 2023 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
worldwide pandemic since 2019, spreading rapidly and posing a significant threat to human …
worldwide pandemic since 2019, spreading rapidly and posing a significant threat to human …
Emerging quinoline‐and quinolone‐based antibiotics in the light of epidemics
Pandemics are large‐scale outbreaks of infectious disease that can greatly increase
morbidity and mortality all the globe. Since past 1990 till twentieth century, these infectious …
morbidity and mortality all the globe. Since past 1990 till twentieth century, these infectious …
Novel guanosine derivatives against MERS CoV polymerase: An in silico perspective
Abstract The Middle East Respiratory Syndrome Coronavirus (MERS CoV), also termed
camel flu, is a new viral infection that first reported in the year 2012 in the Middle East region …
camel flu, is a new viral infection that first reported in the year 2012 in the Middle East region …
Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods
Introduction Despite all the efforts to treat COVID-19, no particular cure has been found for
this virus. Since developing antiviral drugs is a time-consuming process, the most effective …
this virus. Since developing antiviral drugs is a time-consuming process, the most effective …
Molecular dynamics simulation of docking structures of SARS-CoV-2 main protease and HIV protease inhibitors
WB Cardoso, SA Mendanha - Journal of molecular structure, 2021 - Elsevier
In this paper we investigate 10 different HIV protease inhibitors (HPIs) as possible
repurposed-drugs candidates against SARS-CoV-2. To this end, we execute molecular …
repurposed-drugs candidates against SARS-CoV-2. To this end, we execute molecular …
[HTML][HTML] Identification of SARS-CoV-2 RNA-dependent RNA polymerase inhibitors from the major phytochemicals of Nigella sativa: An in silico approach
Abstract The coronavirus disease 2019 (COVID-19), which emerged in December 2019,
continues to be a serious health concern worldwide. There is an urgent need to develop …
continues to be a serious health concern worldwide. There is an urgent need to develop …
Antiviral activities of olive oil apigenin and taxifolin against SARS-CoV-2 RNA-dependent RNA polymerase (RdRP): In silico, pharmacokinetic, ADMET, and in-vitro …
S Selim, M Albqmi, A Alanazi, Y Alruwaili… - Cogent Food & …, 2023 - Taylor & Francis
A novel coronavirus strain called SARS-CoV-2 first appeared in China in December 2019.
Natural products are significant sources of prospective and new antiviral medications, and …
Natural products are significant sources of prospective and new antiviral medications, and …