Radiomics in prostate cancer: An up-to-date review

M Ferro, O de Cobelli, G Musi… - Therapeutic …, 2022 - journals.sagepub.com
Prostate cancer (PCa) is the most common worldwide diagnosed malignancy in male
population. The diagnosis, the identification of aggressive disease, and the post-treatment …

Fascin-1 in cancer cell metastasis: old target-new insights

E Sarantelli, A Mourkakis, LC Zacharia… - International Journal of …, 2023 - mdpi.com
As metastasis is responsible for most cancer-related deaths, understanding the cellular and
molecular events that lead to cancer cell migration and invasion will certainly provide …

Comparative proteome and serum analysis identified FSCN1 as a marker of abiraterone resistance in castration-resistant prostate cancer

A Csizmarik, N Nagy, D Keresztes, M Váradi… - Prostate Cancer and …, 2024 - nature.com
Abstract Background Abiraterone (Abi) is an androgen receptor signaling inhibitor that
significantly improves patients' life expectancy in metastatic prostate cancer (PCa). Despite …

Targeting FSCN1 with an oral small-molecule inhibitor for treating ocular neovascularization

W Bai, JS Ren, M Xia, Y Zhao, JJ Ding, X Chen… - Journal of Translational …, 2023 - Springer
Background Ocular neovascularization is a leading cause of blindness and visual
impairment. While intravitreal anti-VEGF agents can be effective, they do have several …

ΔPSap4# 5 surface-functionalized abiraterone-loaded nanoparticle successfully inhibits carcinogen-induced prostate cancer in mice: a mechanistic investigation

A Al Hoque, D Dutta, B Paul, L Kumari, I Ehsan… - Cancer …, 2023 - Springer
Prostate cancer (PCa) is one of the fatal illnesses among males globally. PCa-treatment
does not include radiotherapy. Chemotherapy eventually causes drug resistance, disease …

The FSCN1 gene rs2966447 variant is associated with increased serum fascin-1 levels and breast cancer susceptibility

AR Abdullah, AMG El-Din, Y Ismail, AA El-Husseiny - Gene, 2024 - Elsevier
Abstract Fascin-1 (FSCN1) is recognized as an actin-binding protein, commonly exhibits up-
regulation in breast cancer (BC) and is crucial for tumor invasion and metastasis. The …

The Role of Fascin-1 in Human Urologic Cancers: A Promising Biomarker or Therapeutic Target?

N Zhang, Q Bian, Y Gao, Q Wang… - … in Cancer Research …, 2023 - journals.sagepub.com
Human cancer statistics show that an increased incidence of urologic cancers such as
bladder cancer, prostate cancer, and renal cell carcinoma. Due to the lack of early markers …

A highly accurate model for screening prostate cancer using propensity index panel of ten genes

S Jain, KPK Malhotra, S Patiyal… - Journal of …, 2023 - liebertpub.com
Prostate-specific antigen (PSA) is a key biomarker commonly used to screen patients for
prostate cancer. A significant number of unnecessary biopsies are performed every year due …