A diverse array of sex determination (SD) mechanisms, encompassing environmental to
genetic, have been found to exist among vertebrates, covering a spectrum from fixed SD …

The transcription factor SOX2 is essential for embryonic development and plays a crucial
role in maintaining the stemness of embryonic cells and various adult stem cell populations …

Aquaculture is one of the most efficient modes of animal protein production and plays an
important role in global food security. Aquaculture animals exhibit extraordinarily diverse …

The discovery of the Sry gene in 1990 triggered a revolution in our understanding of sex
determination. More recently, advances in non-model organisms have been fuelled by the …

Sertoli cells are the orchestrators of spermatogenesis; they support fetal germ cell
commitment to the male pathway and are essential for germ cell development, from …

Spermatogenesis is an extraordinary complex process. The differentiation of spermatogonia
into spermatozoa requires the participation of several cell types, hormones, paracrine …

Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed …

© 2015 Macmillan Publishers Limited. All rights reserved ducts, one of which can form the
uterus and Fallopian tubes, and the other the male internal genital plumbing: the …

The human Y chromosome harbors genes that are responsible for testis development and
also for initiation and maintenance of spermatogenesis in adulthood. The long arm of the Y …

Over the past century, evidence has emerged that endocrine disrupting chemicals (EDCs)
have an impact on reproductive health. An increased frequency of reproductive disorders …