Heart failure in type 2 diabetes mellitus: impact of glucose-lowering agents, heart failure therapies, and novel therapeutic strategies

HC Kenny, ED Abel - Circulation research, 2019 - Am Heart Assoc
Patients with diabetes mellitus have> 2× the risk for developing heart failure (HF; HF with
reduced ejection fraction and HF with preserved ejection fraction). Cardiovascular …

Type 2 diabetes mellitus and heart failure: a scientific statement from the American Heart Association and the Heart Failure Society of America: this statement does not …

SM Dunlay, MM Givertz, D Aguilar, LA Allen, M Chan… - Circulation, 2019 - Am Heart Assoc
Type 2 diabetes mellitus is a risk factor for incident heart failure and increases the risk of
morbidity and mortality in patients with established disease. Secular trends in the …

Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology

PM Seferović, MC Petrie, GS Filippatos… - European journal of …, 2018 - Wiley Online Library
The coexistence of type 2 diabetes mellitus (T2DM) and heart failure (HF), either with
reduced (HFrEF) or preserved ejection fraction (HFpEF), is frequent (30–40% of patients) …

Clinical update: cardiovascular disease in diabetes mellitus: atherosclerotic cardiovascular disease and heart failure in type 2 diabetes mellitus–mechanisms …

CC Low Wang, CN Hess, WR Hiatt, AB Goldfine - Circulation, 2016 - Am Heart Assoc
Cardiovascular disease remains the principal cause of death and disability among patients
with diabetes mellitus. Diabetes mellitus exacerbates mechanisms underlying …

[HTML][HTML] Diabetes and cardiovascular disease: epidemiology, biological mechanisms, treatment recommendations and future research

BM Leon, TM Maddox - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
The incidence of diabetes mellitus (DM) continues to rise and has quickly become one of the
most prevalent and costly chronic diseases worldwide. A close link exists between DM and …

New insights in cardiac β-adrenergic signaling during heart failure and aging

C Lucia, A Eguchi, WJ Koch - Frontiers in pharmacology, 2018 - frontiersin.org
Heart failure (HF) has become increasingly common within the elderly population,
decreasing their survival and overall quality of life. In fact, despite the improvements in …

Heart Failure With Preserved Ejection Fraction and Diabetes: JACC State-of-the-Art Review

K McHugh, AD DeVore, J Wu, RA Matsouaka… - Journal of the American …, 2019 - jacc.org
Heart failure with preserved ejection fraction (HFpEF) is now the most common form of HF,
affecting over 3 million adults in the United States alone. HFpEF is a heterogenous …

The cardio-renal-metabolic connection: a review of the evidence

M Marassi, GP Fadini - Cardiovascular Diabetology, 2023 - Springer
Abstract Type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease
(CKD), are recognized among the most disruptive public health issues of the current century …

[HTML][HTML] SGLT2 inhibitors decrease cardiovascular death and heart failure hospitalizations in patients with heart failure: a systematic review and meta-analysis

R Cardoso, FP Graffunder, CMP Ternes… - …, 2021 - thelancet.com
Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the composite of
heart failure (HF) hospitalizations or cardiovascular mortality among patients with HF …

Diabetes mellitus, blood glucose and the risk of atrial fibrillation: a systematic review and meta-analysis of cohort studies

D Aune, T Feng, S Schlesinger, I Janszky… - Journal of Diabetes and …, 2018 - Elsevier
Background Diabetes and elevated blood glucose have been associated with increased risk
of atrial fibrillation in a number of epidemiological studies, however, the findings have not …