Penile cancer

A Thomas, A Necchi, A Muneer… - Nature Reviews …, 2021 - nature.com
Penile squamous cell carcinoma (PSCC) is a rare cancer with orphan disease designation
and a prevalence of 0.1–1 per 100,000 men in high-income countries, but it constitutes up to …

Prevalence of human papillomavirus DNA and p16INK4a in penile cancer and penile intraepithelial neoplasia: a systematic review and meta-analysis

TB Olesen, FL Sand, CL Rasmussen, V Albieri… - The lancet …, 2019 - thelancet.com
Background Although previous meta-analyses have examined human papillomavirus (HPV)
DNA prevalence in penile cancer, none, to our knowledge, have assessed pooled HPV DNA …

Penile cancer epidemiology and risk factors: a contemporary review

A Douglawi, TA Masterson - Current opinion in urology, 2019 - journals.lww.com
Although Penile cancer can be a debilitating disease, several of the known risk factors are
modifiable. Public health campaigns aimed to increase awareness, promote better hygiene …

The prognostic role of human papillomavirus and p16 status in penile squamous cell carcinoma—a systematic review

K Parza, A Mustasam, F Ionescu, M Paravathaneni… - Cancers, 2023 - mdpi.com
Simple Summary Penile squamous cell carcinoma (PSCC) is a rare and aggressive cancer.
About half of all PSCC cases are thought to be related to human papillomavirus (HPV) or …

Prognostic significance of HPV and p16 status in men diagnosed with penile cancer: a systematic review and meta-analysis

FL Sand, CL Rasmussen, MH Frederiksen… - … Biomarkers & Prevention, 2018 - AACR
It has been shown that human papillomavirus (HPV) and p16 status has prognostic value in
some HPV-associated cancers. However, studies examining survival in men with penile …

Penile cancer: potential target for immunotherapy?

J Vanthoor, G Vos, M Albersen - World Journal of Urology, 2021 - Springer
Abstract Purpose Penile cancer (PeCa) is a rare malignancy with a poor prognosis in
advanced disease. There is still a limited understanding of the biological mediators that are …

The molecular pathogenesis of penile carcinoma—current developments and understanding

A Emmanuel, J Nettleton, N Watkin, DM Berney - Virchows Archiv, 2019 - Springer
Penile squamous cell carcinoma is a rare malignancy with various distinct histological
subtypes, each with distinct appearances, histotypic specific associations with human …

p53 and p16ink4a as predictive and prognostic biomarkers for nodal metastasis and survival in a contemporary cohort of penile squamous cell carcinoma

SK Mohanty, SK Mishra, N Bhardwaj, R Sardana… - Clinical Genitourinary …, 2021 - Elsevier
Background Human papilloma virus (HPV) infection is implicated in a proportion of invasive
squamous cell carcinoma of the penis (PC). A subset of PC involves dysregulation of the …

A comprehensive analysis of penile cancer in the region with the highest worldwide incidence reveals new insights into the disease

AAL Teixeira Júnior, SP da Costa Melo, JD Pinho… - BMC cancer, 2022 - Springer
Background Although penile cancer (PC) is uncommon in developed countries, it is
widespread in developing countries. The state of Maranhão (Northeast, Brazil) has the …

The relationship between human papillomavirus and penile cancer over the past decade: a systematic review and meta-analysis

YB Yu, YH Wang, XC Yang, Y Zhao… - Asian journal of …, 2019 - journals.lww.com
Human papillomavirus (HPV) infection appears to play an important role in the development
of penile cancer (PeCa), but their relationship remains unclear. Therefore, we performed a …