Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents
may induce autoimmunity. It occurs when similarities between foreign and self-peptides …

Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

Type 1 diabetes mellitus (T1DM) is caused by progressive autoimmune-mediated loss of
pancreatic β-cell mass via apoptosis. The onset of T1DM depends on environmental factors …

Type 1 diabetes (T1D) is a chronic autoimmune disease in which destruction or damaging of
the beta-cells in the islets of Langerhans results in insulin deficiency and hyperglycemia. We …

BACKGROUND Multiple laboratory tests are used to diagnose and manage patients with
diabetes mellitus. The quality of the scientific evidence supporting the use of these tests …

A variety of mechanisms have been suggested as the means by which infections can initiate
and/or exacerbate autoimmune diseases. One mechanism is molecular mimicry, where a …

Background: Multiple laboratory tests are used in the diagnosis and management of patients
with diabetes mellitus. The quality of the scientific evidence supporting the use of these …

The development of type 1 diabetes involves a complex interaction between pancreatic β-
cells and cells of both the innate and adaptive immune systems. Analyses of the interactions …

Insulin-dependent diabetes mellitus (IDDM) is a multifactorial autoimmune disease for which
susceptibility is determined by environmental and genetic factors. Inheritance is polygenic …

The most popular hypothesis circulating within and beyond the scientific community is that
viral infections enhance or elicit autoimmune disorders such as type 1 diabetes. Indeed …