Cells are constantly subjected to a spectrum of mechanical cues, such as shear stress,
compression, differential tissue rigidity and strain, to which they adapt by engaging …

The key role of electro-chemical signals in cellular processes had been known for many
years, but more recently the interplay with mechanics has been put in evidence and …

The ability of cells to orient in response to mechanical stimuli is essential to embryonic
development, cell migration, mechanotransduction, and other critical physiologic functions in …

In the presence of anisotropic biochemical or topographical patterns, cells tend to align in
the direction of these cues—a widely reported phenomenon known as" contact guidance." …

Contact guidance—the widely known phenomenon of cell alignment induced by anisotropic
environmental features—is an essential step in the organization of adherent cells, but the …

Cardiac hypertrophy, defined as an increase in mass of the heart, is a complex process
driven by simultaneous changes in hemodynamics, mechanical stimuli, and hormonal …

The response of cells during spreading and motility is dictated by several multi-physics
events, which are triggered by extracellular cues and occur at different time-scales. For this …

Cells are quintessential examples of out-of-equilibrium systems, but they maintain a
homeostatic state over a timescale of hours to days. As a consequence, the statistics of all …

Understanding cardiovascular growth and remodeling (G&R) is fundamental for designing
robust cardiovascular tissue engineering strategies, which enable synthetic or biological …

During embryogenesis, organs undergo dynamic shape transformations that sculpt their
final shape, composition, and function. Despite this, current organ bioprinting approaches …