Cytokines and acute neurodegeneration

SM Allan, NJ Rothwell - Nature Reviews Neuroscience, 2001 - nature.com
Cytokines have been implicated as mediators and inhibitors of diverse forms of
neurodegeneration. They are induced in response to brain injury and have diverse actions …

Thrombospondins as key regulators of synaptogenesis in the central nervous system

WC Risher, C Eroglu - Matrix Biology, 2012 - Elsevier
Thrombospondins (TSPs) are a family of large, oligomeric multidomain glycoproteins that
participate in a variety of biological functions as part of the extracellular matrix (ECM) …

Effects of extracellular matrix‐degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity

SE Meighan, PC Meighan, P Choudhury… - Journal of …, 2006 - Wiley Online Library
Rats learning the Morris water maze exhibit hippocampal changes in synaptic morphology
and physiology that manifest as altered synaptic efficacy. Learning requires structural …

Integrins as receptor targets for neurological disorders

X Wu, DS Reddy - Pharmacology & therapeutics, 2012 - Elsevier
This review focuses on the neurobiology of integrins, pathophysiological roles of integrins in
neuroplasticity and nervous system disorders, and therapeutic implications of integrins as …

Topical review: pathophysiology of Sturge-Weber syndrome

AM Comi - Journal of Child Neurology, 2003 - journals.sagepub.com
Sturge-Weber syndrome is a neurocutaneous disorder classically presenting with a facial
port-wine stain, vascular eye abnormalities, and an ipsilateral occipital leptomeningeal …

[HTML][HTML] Cell adhesion and matricellular support by astrocytes of the tripartite synapse

AEJ Hillen, JPH Burbach, EM Hol - Progress in neurobiology, 2018 - Elsevier
Astrocytes contribute to the formation, function, and plasticity of synapses. Their processes
enwrap the neuronal components of the tripartite synapse, and due to this close interaction …

Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr. Jekyll and Mr. Hyde concept'of Alzheimer's disease or the yin and yang …

T Arendt - Progress in neurobiology, 2003 - Elsevier
Mental actions are based on the dynamic organization of neuronal networks. In particular,
phylogenetically young brain areas (eg, cortical associative circuits) involved in the …

In vivo roles for matrix metalloproteinase-9 in mature hippocampal synaptic physiology and plasticity

O Bozdagi, V Nagy, KT Kwei… - Journal of …, 2007 - journals.physiology.org
Extracellular proteolysis is an important regulatory nexus for coordinating synaptic functional
and structural plasticity, but the identity of such proteases is incompletely understood. Matrix …

Sturge–Weber syndrome

AM Comi - Handbook of clinical neurology, 2015 - Elsevier
Sturge–Weber syndrome is the third most common neurocutaneous disorder, after
neurofibromatosis and tuberous sclerosis, and impacts approximately 1 in 20 000 live births …

[HTML][HTML] Extracellular matrix control of dendritic spine and synapse structure and plasticity in adulthood

AD Levy, MH Omar, AJ Koleske - Frontiers in neuroanatomy, 2014 - frontiersin.org
Dendritic spines are the receptive contacts at most excitatory synapses in the central
nervous system. Spines are dynamic in the developing brain, changing shape as they …