Multi-cellular aggregates, a model for living matter
This review presents the different physical descriptions of cell assemblies. After a short
presentation of discrete models, very popular in studies of epithelial tissues, we focus more …
presentation of discrete models, very popular in studies of epithelial tissues, we focus more …
Self-assembly of tessellated tissue sheets by expansion and collision
Tissues do not exist in isolation—they interact with other tissues within and across organs.
While cell-cell interactions have been intensely investigated, less is known about tissue …
While cell-cell interactions have been intensely investigated, less is known about tissue …
High-throughput cell and spheroid mechanics in virtual fluidic channels
MH Panhwar, F Czerwinski, VAS Dabbiru… - Nature …, 2020 - nature.com
Microfluidics by soft lithography has proven to be of key importance for biophysics and life
science research. While being based on replicating structures of a master mold using …
science research. While being based on replicating structures of a master mold using …
Mechanical regulation of epithelial tissue homeostasis
S Kaliman, M Hubert, C Wollnik, L Nuić, D Vurnek… - Physical Review X, 2021 - APS
Despite recent efforts to understand homeostasis in epithelial tissues, there are many
unknowns surrounding this steady state. It is considered to be regulated by …
unknowns surrounding this steady state. It is considered to be regulated by …
Cell stiffening is a label-free indicator of reactive oxygen species-induced intracellular acidification
Y Komaragiri, RH Pires, S Spiegler, HT Dau… - Communications …, 2024 - nature.com
Reactive oxygen species (ROS) are important secondary messengers involved in a variety
of cellular processes, including activation, proliferation, and differentiation. Hydrogen …
of cellular processes, including activation, proliferation, and differentiation. Hydrogen …
Capturing the mechanosensitivity of cell proliferation in models of epithelium
K Höllring, L Nuić, L Rogić, S Kaliman, S Gehrer… - Proceedings of the …, 2024 - pnas.org
Despite the primary role of cell proliferation in tissue development and homeostatic
maintenance, the interplay between cell density, cell mechanoresponse, and cell growth …
maintenance, the interplay between cell density, cell mechanoresponse, and cell growth …
Instability and fingering of interfaces in growing tissue
T Büscher, AL Diez, G Gompper… - New Journal of Physics, 2020 - iopscience.iop.org
Interfaces in tissues are ubiquitous, both between tissue and environment as well as
between populations of different cell types. The propagation of an interface can be driven …
between populations of different cell types. The propagation of an interface can be driven …
Tissue evolution: Mechanical interplay of adhesion, pressure, and heterogeneity
The evolution of various competing cell types in tissues, and the resulting persistent tissue
population, is studied numerically and analytically in a particle-based model of active …
population, is studied numerically and analytically in a particle-based model of active …
Self-assembly of tessellated tissue sheets by growth and collision
Tissues do not exist in isolation–they interact with other tissues within and across organs.
While cell-cell interactions have been intensely investigated, less is known about tissue …
While cell-cell interactions have been intensely investigated, less is known about tissue …
A competitive advantage through fast dead matter elimination in confined cellular aggregates
Competition of different species or cell types for limited space is relevant in a variety of
biological processes such as biofilm development, tissue morphogenesis and tumor growth …
biological processes such as biofilm development, tissue morphogenesis and tumor growth …