The vascular endothelial growth factor receptor (VEGFR) system is the key component for
controlling angiogenesis in cancer cells. Blocking vascular endothelial growth factor …

American Trypanosomiasis, also known as Chagas disease, is caused by the protozoan
Trypanosoma cruzi and exhibits limited options for treatment. Natural products offer various …

Cisplatin (CP) is an antineoplastic agent used to treat solid tumors, that has high
nephrotoxicity caused by physiologic, hemodynamic, and biochemical alterations. Some …

Background Temozolomide (TMZ) is the first-line chemotherapeutic drug for gliomas
treatment. However, the clinical efficacy of TMZ in glioma patients was very limited …

BACKGROUND: Andrographis paniculata has anti-inflammatory, anti-cancer, and
immunomodulatory effects. Intercellular adhesion molecule-1 (ICAM-1) and E-selectin are …

Inflammation induced by angiotensin II (Ang II) is a key event in the progression of numerous
cardiovascular diseases. Astragaloside IV (AS‐IV), a glycoside extracted from Astragalus …

Objectives Drug-induced cardiac injury is a potentially preventable cause of heart failure.
Cisplatin (CIS) is a widely used chemotherapeutic agent complicated with cardiotoxicity that …

Introduction Cisplatin (cis‐diamminedichloroplatinum II, CDDP), a drug widely used for
cancer worldwide, may affect erectile function, but its side effects have not received enough …

Chemotherapy causes sensory disturbances in cancer patients that results in neuropathies
and pain. As cancer survivorships has dramatically increased over the past 10 years, pain …

Sepsis is a complex disease involving multiple organs, with high morbidity and mortality
rates, and high patient admission rates to intensive care units. The pathogenesis of the …