Cytokinesis, the final step in cell division, partitions the contents of a single cell into two. In
animal cells, cytokinesis occurs through cortical remodeling orchestrated by the anaphase …

Cytokinesis is the process by which mitotic cells physically split in two following
chromosome segregation. Dividing animal cells first ingress a cytokinetic furrow and then …

Cells actively produce contractile forces for a variety of processes including cytokinesis and
motility. Contractility is known to rely on myosin II motors which convert chemical energy …

Cytokinesis is accomplished by constriction of a cortical contractile ring. We show that during
the early embryonic divisions in C. elegans, ring constriction occurs in two phases—an initial …

Cytokinesis involves constriction of a contractile actomyosin ring. The mechanisms
generating ring tension and setting the constriction rate remain unknown because the …

Collective cell migration in cohesive units is vital for tissue morphogenesis, wound repair,
and immune response. While the fundamental driving forces for collective cell motion stem …

We present a physical analysis of the dynamics and mechanics of contractile actin rings. In
particular, we analyze the dynamics of ring contraction during cytokinesis in the …

The cytokinetic ring is essential for separating daughter cells during division. It consists of
actin filaments and myosin motors that are generally assumed to organize as sarcomeres …

This article is a critical review of computational techniques used to model, analyse and
simulate signalling networks. We propose a conceptual framework, and discuss the role of …

Cytoskeletal systems are networks of polymers found in all eukaryotic and many prokaryotic
cells. Their purpose is to transmit and integrate information across cellular dimensions and …