Respiratory viral infections have been a long-standing global burden ranging from seasonal
recurrences to the unexpected pandemics. The yearly hospitalizations from seasonal …

Vaccination remains the most effective prophylactic intervention for infectious disease in the
healthcare professional's toolkit. However, the efficacy and effectiveness of vaccines …

The vast majority of currently licensed human vaccines work on the basis of long-term
protective antibody responses. It is now conceivable that an antibody-dependent HIV …

Despite long-term investment, influenza continues to be a significant worldwide problem.
The cornerstone of protection remains vaccination, and approved vaccines seek to elicit a …

Background Influenza vaccine effectiveness (VE) is generally interpreted in the context of
vaccine match/mismatch to circulating strains with evolutionary drift in the latter invoked to …

Background. Circulating A/H3N2 influenza viruses drifted significantly after strain selection
for the 2014–2015 vaccines. Also in 2014–2015, the Advisory Committee on Immunization …

Abstract Background. During the 2012–2013 influenza season, there was cocirculation of
influenza A (H3N2) and 2 influenza B lineage viruses in the United States. Methods. Patients …

The effect of prior influenza vaccination history on vaccine effectiveness was assessed in a
community cohort over 8 seasons. Current-and previous-season vaccination generated …

The identification of key “driver” groups in influenza epidemics is of much interest for the
implementation of effective public health response strategies, including vaccination …

Although influenza vaccination is recommended for all adults annually, the incidence of
vaccine failure, defined as weak or absent increase in neutralizing Ab titers, is increased in …