Pompe disease (PD) is a neuromuscular disorder caused by a deficiency of acid alpha-
glucosidase (GAA)–a lysosomal enzyme responsible for hydrolyzing glycogen. GAA …

Respiratory diseases are leading causes of death and disability in the world. While early
diagnosis is key, this has proven difficult due to the lack of sensitive and non-invasive tools …

Abstract Purpose The interaction between 129Xe atoms and pulmonary capillary red blood
cells provides cardiogenic signal oscillations that display sensitivity to precapillary and …

Although patients with SSc-PAH and IPAH present with similar symptoms, there are
significant differences between these two forms of PAH that warrant further investigation and …

Introduction Hyperpolarized 129Xe MRI and spectroscopy is a rapidly growing technique for
assessing lung function, with applications in a wide range of obstructive, restrictive, and …

This book chapter covers relevant articles published in peer-reviewed journals in 2022 in
the field of NMR spectroscopy of small molecules in solution. Articles that appeared in 2022 …

BACKGROUND There is currently no sensitive, non-invasive method of screening for
chronic lung allograft dysfunction (CLAD), the primary barrier to long-term survival after lung …

This chapter focuses on the literature published in 2022, covering hyperpolarisation
techniques associated with NMR. The literature reviewed relates to the hyperpolarisation …

129 Xe dynamic spectroscopy combined with 129 Xe gas exchange MRI can detect both pre-
and postcapillary pulmonary hypertension (PH). However, reliance on whole lung …

Abstract Hyperpolarized (HP) 129Xe Magnetic Resonance Imaging (MRI) is a promising
approach for the non-invasive diagnosis of pulmonary pathophysiology and has recently …