[HTML][HTML] Mechanisms of manganese-induced neurotoxicity and the pursuit of neurotherapeutic strategies
E Pajarillo, I Nyarko-Danquah, A Digman… - Frontiers in …, 2022 - frontiersin.org
Chronic exposure to elevated levels of manganese via occupational or environmental
settings causes a neurological disorder known as manganism, resembling the symptoms of …
settings causes a neurological disorder known as manganism, resembling the symptoms of …
[HTML][HTML] Probucol will become a new model for treating cerebral infarction with a high risk of hemorrhage: A narrative review
L Lang, J Zhang, D Zheng, H Gao - Brain Circulation, 2023 - journals.lww.com
Lipid-lowering agents are relevant in stroke prevention. Probucol (PU) is an antioxidative
and lipid-lowering drug that has been used to treat atherosclerotic cardiovascular diseases …
and lipid-lowering drug that has been used to treat atherosclerotic cardiovascular diseases …
[HTML][HTML] Probucol protects against brain damage caused by intra-neural pyroptosis in rats with vascular dementia through inhibition of the Syk/Ros pathway
J Zhu, J Du, W Kou, C Liu, J Fan, Z Zhu, L Deng… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Background: Neuronal injury in chronic cerebral hypoperfusion (CCH) is the main
pathogenic factor of vascular dementia (VD). Clinically, there isn'ta drug specifically for VD; …
pathogenic factor of vascular dementia (VD). Clinically, there isn'ta drug specifically for VD; …
Probucol neuroprotection against manganese-induced damage in adult Wistar rat brain slices
SC Del Rio Naiz, KG Varela… - Toxicology and …, 2023 - journals.sagepub.com
Manganese (Mn) is an abundant element used for commercial purposes and is essential for
the proper function of biological systems. Chronic exposure to high Mn concentrations …
the proper function of biological systems. Chronic exposure to high Mn concentrations …
Signal Transduction Associated with Mn-induced Neurological Dysfunction
X Zheng, Y Fang, J Lin, J Luo, S Li, M Aschner… - … Trace Element Research, 2023 - Springer
Manganese (Mn) is a heavy metal that occurs widely in nature and has a vital physiological
role in growth and development. However, excessive exposure to Mn can cause …
role in growth and development. However, excessive exposure to Mn can cause …
Neuroprotective effect of vitamin D on behavioral and oxidative parameters of male and female adult wistar rats exposed to mancozeb (manganese/zinc ethylene bis …
JC Favarin, A Basotti, AR Baptistella, A Mantovani… - Molecular …, 2023 - Springer
The constant exposure of rural workers to pesticides is a serious public health problem.
Mancozeb (MZ) is a pesticide linked to hormonal, behavioral, genetic, and …
Mancozeb (MZ) is a pesticide linked to hormonal, behavioral, genetic, and …
Probucol will become a New Model for Treating Cerebral Infarction with a High Risk of Hemorrhage
L Lang, J Zhang, H Gao - Current Medicinal Chemistry, 2024 - ingentaconnect.com
Antiplatelet, antihypertensive, and lipid-lowering agents are the three foundational agents
for secondary prevention of ischemic stroke, among which lipid-lowering is one of the most …
for secondary prevention of ischemic stroke, among which lipid-lowering is one of the most …
Neuroprotective Effects of Probucol against Rotenone-Induced Toxicity via Suppression of Reactive Oxygen Species Production in SH-SY5Y Cells
T Takeo, M Miyake, H Mizuno - Biological and Pharmaceutical …, 2024 - jstage.jst.go.jp
Probucol is a hyperlipidemic drug with antioxidant properties. It has been reported to prevent
mitochondrial dysfunction, reduce oxidative stress, and suppress neurotoxicity in …
mitochondrial dysfunction, reduce oxidative stress, and suppress neurotoxicity in …