Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases
L Recinella, G Orlando, C Ferrante… - Frontiers in …, 2020 - frontiersin.org
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …
and complex endocrine organ, which produces and secretes several adipokines, including …
Insulin and insulin receptors in adipose tissue development
A Cignarelli, VA Genchi, S Perrini… - International journal of …, 2019 - mdpi.com
Insulin is a major endocrine hormone also involved in the regulation of energy and lipid
metabolism via the activation of an intracellular signaling cascade involving the insulin …
metabolism via the activation of an intracellular signaling cascade involving the insulin …
[HTML][HTML] Effects of intermittent fasting on the circulating levels and circadian rhythms of hormones
Intermittent fasting has become an increasingly popular strategy in losing weight and
associated reduction in obesity-related medical complications. Overwhelming studies …
associated reduction in obesity-related medical complications. Overwhelming studies …
Vaspin in obesity and diabetes: pathophysiological and clinical significance
M Blüher - Endocrine, 2012 - Springer
Vaspin (visceral adipose tissue-derived serpin; serpinA12) was originally identified as an
adipokine, which is predominantly secreted from visceral adipose tissue in Otsuka Long …
adipokine, which is predominantly secreted from visceral adipose tissue in Otsuka Long …
Adipose tissue as an endocrine organ
C McGown, A Birerdinc, ZM Younossi - Clinics in liver disease, 2014 - liver.theclinics.com
Obesity is currently one the largest epidemics in the industrialized world. It is also the nexus
on which numerous costly chronic diseases, such as hypertension, hyperlipidemia, T2D …
on which numerous costly chronic diseases, such as hypertension, hyperlipidemia, T2D …
Role of omentin, vaspin, cardiotrophin-1, TWEAK and NOV/CCN3 in obesity and diabetes development
X Escoté, S Gómez-Zorita, M López-Yoldi… - International journal of …, 2017 - mdpi.com
Adipose tissue releases bioactive mediators called adipokines. This review focuses on the
effects of omentin, vaspin, cardiotrophin-1, Tumor necrosis factor-like Weak Inducer of …
effects of omentin, vaspin, cardiotrophin-1, Tumor necrosis factor-like Weak Inducer of …
Vaspin inhibits kallikrein 7 by serpin mechanism
JT Heiker, N Klöting, P Kovacs, EB Kuettner… - Cellular and Molecular …, 2013 - Springer
The molecular target of the adipokine vaspin (visceral adipose tissue-derived serpin;
serpinA12) and its mode of action are unknown. Here, we provide the vaspin crystal …
serpinA12) and its mode of action are unknown. Here, we provide the vaspin crystal …
Central vaspin administration acutely reduces food intake and has sustained blood glucose-lowering effects
N Klöting, P Kovacs, M Kern, JT Heiker, M Fasshauer… - Diabetologia, 2011 - Springer
Aims/hypothesis Vaspin (visceral adipose tissue-derived serpin) was first identified as an
adipokine in a rat model of type 2 diabetes, in which it is predominantly secreted from …
adipokine in a rat model of type 2 diabetes, in which it is predominantly secreted from …
Circadian rhythm of circulating fibroblast growth factor 21 is related to diurnal changes in fatty acids in humans
BACKGROUND Fibroblast growth factor (FGF) 21 is an endocrine factor actively involved in
glucose and lipid metabolism in rodents. However, little is known about its physiological …
glucose and lipid metabolism in rodents. However, little is known about its physiological …
The role of vaspin in the development of metabolic and glucose tolerance disorders and atherosclerosis
R Dimova, T Tankova - BioMed research international, 2015 - Wiley Online Library
In recent years, most research efforts have been focused on studying insulin‐sensitizing
adipokines. One of the most recently discovered adipokines is vaspin, a visceral adipose …
adipokines. One of the most recently discovered adipokines is vaspin, a visceral adipose …