Extracellular Matrix in Vascular Disease, Part 2/4: JACC Focus Seminar

J Barallobre-Barreiro, B Loeys, M Mayr… - Journal of the American …, 2020 - jacc.org
Medium-sized and large arteries consist of 3 layers: the tunica intima, tunica media, and
tunica adventitia. The tunica media accounts for the bulk of the vessel wall and is the chief …

Adopting artificial intelligence in cardiovascular medicine: A scoping review

H Makimoto, T Kohro - Hypertension Research, 2024 - nature.com
Recent years have witnessed significant transformations in cardiovascular medicine, driven
by the rapid evolution of artificial intelligence (AI). This scoping review was conducted to …

Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases

A Georges, ML Yang, TE Berrandou, MK Bakker… - Nature …, 2021 - nature.com
Fibromuscular dysplasia (FMD) is an arteriopathy associated with hypertension, stroke and
myocardial infarction, affecting mostly women. We report results from the first genome-wide …

FMD and SCAD: sex-biased arterial diseases with clinical and genetic pleiotropy

ESH Kim, J Saw, D Kadian-Dodov, M Wood… - Circulation …, 2021 - Am Heart Assoc
Multifocal fibromuscular dysplasia (FMD) and spontaneous coronary artery dissection are
both sex-biased diseases disproportionately affecting women over men in a 9: 1 ratio …

Network medicine in Cardiovascular Research

LY Lee, AK Pandey, BA Maron… - Cardiovascular …, 2021 - academic.oup.com
The ability to generate multi-omics data coupled with deeply characterizing the clinical
phenotype of individual patients promises to improve understanding of complex …

The complex genetic basis of fibromuscular dysplasia, a systemic arteriopathy associated with multiple forms of cardiovascular disease

A Georges, N Bouatia-Naji - Clinical Science, 2022 - portlandpress.com
Artery stenosis is a common cause of hypertension and stroke and can be due to
atherosclerosis accumulation in the majority of cases and in a small fraction of patients to …

Current progress in clinical, molecular, and genetic aspects of adult fibromuscular dysplasia

A Persu, P Dobrowolski, HL Gornik… - Cardiovascular …, 2022 - academic.oup.com
Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease that may involve
medium-sized muscular arteries throughout the body. The majority of FMD patients are …

The year in cardiovascular medicine 2020: digital health and innovation

C Antoniades, FW Asselbergs… - European heart …, 2021 - academic.oup.com
Advances in digital health and particularly in artificial intelligence (AI) have led us very close
to the true implementation of personalized medicine. The year 2020 has brought an …

Spontaneous coronary artery dissection and fibromuscular dysplasia: vasculopathies with a predilection for women

SE Iismaa, S Hesselson, L McGrath-Cadell… - Heart, Lung and …, 2021 - Elsevier
The burden of cardiovascular disease in women is being increasingly appreciated.
Nevertheless, both clinicians and the general public are largely unaware that cardiovascular …

Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia

A Georges, J Albuisson, T Berrandou… - Cardiovascular …, 2021 - academic.oup.com
Aims Fibromuscular dysplasia (FMD) and spontaneous coronary artery dissection (SCAD)
are related, non-atherosclerotic arterial diseases mainly affecting middle-aged women. Little …