Cystic kidneys are common causes of end-stage renal disease, both in children and in
adults. Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary
kidney disease and one of the most common causes of end-stage kidney disease. Multiple …

Autosomal-dominant polycystic kidney disease (ADPKD) affects up to 12 million individuals
and is the fourth most common cause for renal replacement therapy worldwide. There have …

Background The course of autosomal dominant polycystic kidney disease (ADPKD) is often
associated with pain, hypertension, and kidney failure. Preclinical studies indicated that …

The rate of renal disease progression varies widely among patients with autosomal
dominant polycystic kidney disease (ADPKD), necessitating optimal patient selection for …

Focal liver lesions (FLL) have been a common reason for consultation faced by
gastroenterologists and hepatologists. The increasing and widespread use of imaging …

Ciliopathies comprise a group of disorders associated with genetic mutations encoding
defective proteins, which result in either abnormal formation or function of cilia. As cilia are a …

Results After a mean follow-up of 7.9 years, stage 3 CKD was attained in 30.7% of the
enrollees. Using baseline htTKV, negative correlations with GFR increased from− 0.22 at …

Cholangiocytes (ie, the epithelial cells that line the bile ducts) are an important subset of
liver cells. They are actively involved in the modification of bile volume and composition, are …

Polycystic kidney disease (PKD) is a leading cause of ESRD worldwide. In PKD, excessive
cell proliferation and fluid secretion, pathogenic interactions of mutated epithelial cells with …