The functions, purposes, and roles of metallothioneins have been the subject of
speculations since the discovery of the protein over 60 years ago. This article guides …

Zinc is recognized as an essential trace metal required for human health; its deficiency is
strongly associated with neuronal and immune system defects. Although zinc is a redox-inert …

The solution and complexation chemistry of zinc ions is the basis for zinc biology. In living
organisms, zinc is redox-inert and has only one valence state: Zn (II). Its coordination …

Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Evidence for the importance of zinc for all immune cells and for mounting an efficient and
balanced immune response to various environmental stressors has been accumulating in …

In the last decade, we witnessed discoveries that established Zn2+ as a second major
signalling metal ion in the transmission of information within cells and in communication …

P2X receptors are trimeric, non-selective cation channels activated by extracellular ATP. The
P2X 7 receptor subtype is a pharmacological target because of involvement in apoptotic …

Recent discoveries in zinc biology provide a new platform for discussing the primary
physiological functions of mammalian metallothioneins (MTs) and their exquisite zinc …

Zinc fingers (ZFs) are among the most structurally diverse protein domains. They interact
with nucleic acids, other proteins and lipids to facilitate a multitude of biological processes …

The development of aggregation-induced emission enhancement (AIEE) active nanoprobes
without any synthetic complication for solution-state and organic thin-film transistor (OTFT) …