Control of cerebral blood flow by blood gases

J Duffin, DJ Mikulis, JA Fisher - Frontiers in Physiology, 2021 - frontiersin.org
Cerebrovascular reactivity can be measured as the cerebrovascular flow response to a
hypercapnic challenge. The many faceted responses of cerebral blood flow to combinations …

A mathematical model of cerebral blood flow control in anaemia and hypoxia

J Duffin, GMT Hare, JA Fisher - The Journal of physiology, 2020 - Wiley Online Library
Key points The control of cerebral blood flow in hypoxia, anaemia and hypocapnia is
reviewed with an emphasis on the links between cerebral blood flow and possible stimuli. A …

[HTML][HTML] Using novel magnetic resonance imaging methods to predict stroke risk in individuals with sickle cell anemia

LC Jordan, AA Kassim, KL Wilkerson, CA Lee… - … /oncology and stem cell …, 2020 - Elsevier
Sickle cell anemia (SCA) is a well-characterized monogenetic disorder with a high
prevalence of cerebral vasculopathy, silent cerebral infarcts, and strokes. A significant …

The Physiological Basis of Cerebrovascular Reactivity Measurements

O Sobczyk, J Duffin, JA Fisher, DJ Mikulis - … Methodological Advances and …, 2021 - Springer
The brain requires a continuous supply of oxygen, which in normal environments is directly
related to cerebral blood flow. Accordingly, a number of mechanisms are in place to …