Abstract In 1964, Vincent Allfrey and colleagues reported the identification of histone
acetylation and with deep insight proposed a regulatory role for this protein modification in …

The nucleosomal subunit organization of chromatin provides a multitude of functions.
Nucleosomes elicit an initial∼ 7-fold linear compaction of genomic DNA. They provide a …

Plants can be primed for more rapid and robust activation of defence to biotic or abiotic
stress. Priming follows perception of molecular patterns of microbes or plants, recognition of …

This article reviews the effects of the short-chain fatty acid butyrate on histone deacetylase
(HDAC) activity. Sodium butyrate has multiple effects on cultured mammalian cells that …

Acetylation of internal lysine residues of core histone N‐terminal domains has been found
correlatively associated with transcriptional activation in eukaryotes for more than three …

The organization of eukaryotic chromatin has a major impact on all nuclear processes
involving DNA substrates. Gene expression is affected by the positioning of individual …

Priming of defence genes for amplified response to secondary stress can be induced by
application of the plant hormone salicylic acid or its synthetic analogue acibenzolar S …

p300/CBP transcriptional co-activator proteins play a central role in co-ordinating and
integrating multiple signal-dependent events with the transcription apparatus, allowing the …

In eukaryotes, transcription of genes by RNA polymerase II yields messenger RNA
intermediates from which protein products are synthesized. Transcriptional enhancers are …

▪ Abstract The past decade has seen an explosive increase in information about regulation
of eukaryotic gene transcription, especially for protein-coding genes. The most striking …