[HTML][HTML] Unraveling the mystery of efficacy in Chinese medicine formula: new approaches and technologies for research on pharmacodynamic substances
Y Li, Z Lin, Y Wang, S Ju, H Wu, H Jin, S Ma… - Arabian Journal of …, 2022 - Elsevier
Traditional Chinese medicine (TCM) is the key to unlock treasures of Chinese civilization.
TCM and its compound play a beneficial role in medical activities to cure diseases …
TCM and its compound play a beneficial role in medical activities to cure diseases …
Strategies in medicinal chemistry to discover new hit compounds against ebola virus: Challenges and perspectives in drug discovery
IJ dos Santos Nascimento… - Mini Reviews in …, 2022 - ingentaconnect.com
Ebola Virus (EBOV) is an infectious disease that mainly affects the cardiovascular system. It
belongs to the Filoviridae family, consisting of filamentous envelopes and non-segmented …
belongs to the Filoviridae family, consisting of filamentous envelopes and non-segmented …
Anthocyanin derivatives as potent inhibitors of SARS-CoV-2 main protease: An in-silico perspective of therapeutic targets against COVID-19 pandemic
Z Fakhar, B Faramarzi, S Pacifico… - Journal of Biomolecular …, 2021 - Taylor & Francis
A new pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
spread worldwide and become pandemic with thousands new deaths and infected cases …
spread worldwide and become pandemic with thousands new deaths and infected cases …
Molecular dynamics simulation of docking structures of SARS-CoV-2 main protease and HIV protease inhibitors
WB Cardoso, SA Mendanha - Journal of molecular structure, 2021 - Elsevier
In this paper we investigate 10 different HIV protease inhibitors (HPIs) as possible
repurposed-drugs candidates against SARS-CoV-2. To this end, we execute molecular …
repurposed-drugs candidates against SARS-CoV-2. To this end, we execute molecular …
In silico approach of naringin as potent phosphatase and tensin homolog (PTEN) protein agonist against prostate cancer
Prostate cancer (PC) is one of the major impediments affecting men, which leads
approximately 31,620 deaths in both developing and developed countries. Although some …
approximately 31,620 deaths in both developing and developed countries. Although some …
EBOLApred: A machine learning-based web application for predicting cell entry inhibitors of the Ebola virus
J Adams, K Agyenkwa-Mawuli, O Agyapong… - … Biology and Chemistry, 2022 - Elsevier
Ebola virus disease (EVD) is a highly virulent and often lethal illness that affects humans
through contact with the body fluid of infected persons. Glycoprotein and matrix protein VP40 …
through contact with the body fluid of infected persons. Glycoprotein and matrix protein VP40 …
[HTML][HTML] Discovery of a potent candidate for ret-specific non-small-cell lung cancer—a combined in silico and in vitro strategy
Rearranged during transfection (RET) is a tyrosine kinase oncogenic receptor, activated in
several cancers including non-small-cell lung cancer (NSCLC). Multiple kinase inhibitors …
several cancers including non-small-cell lung cancer (NSCLC). Multiple kinase inhibitors …
Discovery of small molecule inhibitors of chikungunya virus proteins (nsP2 and E1) using in silico approaches
Chikungunya virus (CHIKV) has emerged as a major viral threat, affecting over a million
people worldwide per year. It is a vector borne disease transmitted to the human by Ades …
people worldwide per year. It is a vector borne disease transmitted to the human by Ades …
Exploration of Computational Aids for Effective Drug Designing and Management of Viral Diseases: A Comprehensive Review
T Khan, S Raza - Current Topics in Medicinal Chemistry, 2023 - ingentaconnect.com
Background: Microbial diseases, specifically originating from viruses are the major cause of
human mortality all over the world. The current COVID-19 pandemic is a case in point …
human mortality all over the world. The current COVID-19 pandemic is a case in point …
Combination of bendamustine-azacitidine against Syk target of breast cancer: an in silico study
S Muthumanickam, B Ramachandran… - Journal of …, 2023 - Taylor & Francis
Breast cancer (BC) is the most serious and second leading cause of death in women
worldwide. When breast cancer is diagnosed and treated early, the chance of long-term …
worldwide. When breast cancer is diagnosed and treated early, the chance of long-term …