[HTML][HTML] Protein domain identification methods and online resources

Y Wang, H Zhang, H Zhong, Z Xue - Computational and structural …, 2021 - Elsevier
Protein domains are the basic units of proteins that can fold, function, and evolve
independently. Knowledge of protein domains is critical for protein classification …

Immunoinformatics: In Silico Approaches and Computational Design of a Multi-epitope, Immunogenic Protein

AA Bahrami, Z Payandeh, S Khalili… - International reviews …, 2019 - Taylor & Francis
Immunoinformatics is a new critical field with several tools and databases that conduct the
eyesight of experimental selection and facilitate analysis of the great amount of immunologic …

FUpred: detecting protein domains through deep-learning-based contact map prediction

W Zheng, X Zhou, Q Wuyun, R Pearce, Y Li… - …, 2020 - academic.oup.com
Motivation Protein domains are subunits that can fold and function independently. Correct
domain boundary assignment is thus a critical step toward accurate protein structure and …

SWORD2: hierarchical analysis of protein 3D structures

G Cretin, T Galochkina, Y Vander Meersche… - Nucleic acids …, 2022 - academic.oup.com
Understanding the functions and origins of proteins requires splitting these macromolecules
into fragments that could be independent in terms of folding, activity, or evolution. For that …

ThreaDom: extracting protein domain boundary information from multiple threading alignments

Z Xue, D Xu, Y Wang, Y Zhang - Bioinformatics, 2013 - academic.oup.com
Motivation: Protein domains are subunits that can fold and evolve independently.
Identification of domain boundary locations is often the first step in protein folding and …

DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning

J Eickholt, X Deng, J Cheng - BMC bioinformatics, 2011 - Springer
Background Accurate identification of protein domain boundaries is useful for protein
structure determination and prediction. However, predicting protein domain boundaries from …

DNN-Dom: predicting protein domain boundary from sequence alone by deep neural network

Q Shi, W Chen, S Huang, F Jin, Y Dong, Y Wang… - …, 2019 - academic.oup.com
Motivation Accurate delineation of protein domain boundary plays an important role for
protein engineering and structure prediction. Although machine-learning methods are …

ThreaDomEx: a unified platform for predicting continuous and discontinuous protein domains by multiple-threading and segment assembly

Y Wang, J Wang, R Li, Q Shi, Z Xue… - Nucleic acids …, 2017 - academic.oup.com
We develop a hierarchical pipeline, ThreaDomEx, for both continuous domain (CD) and
discontinuous domain (DCD) structure predictions. Starting from a query sequence …

Malphite: A convolutional neural network and ensemble learning based protein secondary structure predictor

Y Li, T Shibuya - 2015 IEEE International Conference on …, 2015 - ieeexplore.ieee.org
We developed a convolution neural networks (CNN) and ensemble learning based method,
called Malphite, to predict protein secondary structures. Maphite has three sub-models: the …

Res-Dom: predicting protein domain boundary from sequence using deep residual network and Bi-LSTM

L Wang, H Zhong, Z Xue, Y Wang - Bioinformatics Advances, 2022 - academic.oup.com
Motivation Protein domains are the basic units of proteins that can fold, function and evolve
independently. Protein domain boundary partition plays an important role in protein structure …