Plants produce interesting secondary metabolites that are a valuable source of both
medicines for human use, along with significant advantages for the manufacturer species …

Dental pathology remains a global health problem affecting both children and adults. The
most important dental diseases are dental caries and periodontal pathologies. The main …

Novel multifunctional bio-based nanofibrous mats were prepared which contain the
commonly used pain reducing local anesthetic benzocaine (BZC) and the in situ pH …

Acidic environments, such as in inflamed tissues, favor the charged form of local anesthetics
(LA). Hence, these drugs show less cell permeation and diminished potency. Since the …

The production of alkaloids in the intact plant is usually low, and some of them are tissue-
specific and growth stage–specific. In this study, the total alkaloid content (TAC) in Polyalthia …

The present study aimed to detect the bioactive metabolites from Ocimum forskolei aerial
parts which are responsible for the local anaesthetic activity of the ethyl acetate fraction …

Antibiotics are the chemical substances secreted by microorganisms used for treating
several types of other microbial diseases. However, a repeated as well as regular use of the …

Lead toxicity remains one of the most important occupational and environmental health
problems with characteristic features that are incompatible with life. Considering the …

Objectives Local and general anaesthetics currently used in clinical practice are not
absolutely safe and efficacious. Hence two or more drugs are used for induction and …

Amine-containing drugs often show poor pharmacological properties, but these
disadvantages can be overcome by using a prodrug approach involving self-immolative …