An overview of the medicinally important plant type III PKS derived polyketides
Plants produce interesting secondary metabolites that are a valuable source of both
medicines for human use, along with significant advantages for the manufacturer species …
medicines for human use, along with significant advantages for the manufacturer species …
Vegetal compounds as sources of prophylactic and therapeutic agents in dentistry
RA Milutinovici, D Chioran, R Buzatu, I Macasoi… - Plants, 2021 - mdpi.com
Dental pathology remains a global health problem affecting both children and adults. The
most important dental diseases are dental caries and periodontal pathologies. The main …
most important dental diseases are dental caries and periodontal pathologies. The main …
A multifunctional electrospun and dual nano-carrier biobased system for simultaneous detection of pH in the wound bed and controlled release of benzocaine
M Kurečič, T Maver, N Virant, A Ojstršek, L Gradišnik… - Cellulose, 2018 - Springer
Novel multifunctional bio-based nanofibrous mats were prepared which contain the
commonly used pain reducing local anesthetic benzocaine (BZC) and the in situ pH …
commonly used pain reducing local anesthetic benzocaine (BZC) and the in situ pH …
Capsaicin-cyclodextrin complex enhances mepivacaine targeting and improves local anesthesia in inflamed tissues
VM Couto, L de Oliveira-Nascimento… - International Journal of …, 2020 - mdpi.com
Acidic environments, such as in inflamed tissues, favor the charged form of local anesthetics
(LA). Hence, these drugs show less cell permeation and diminished potency. Since the …
(LA). Hence, these drugs show less cell permeation and diminished potency. Since the …
Prolonged incubation of callus on auxin herbicide 2,4-D displayed significant effect on alkaloid production in callus of the woody medicinal plant Polyalthia bullata
MAK Zaman, AM Azzeme, IK Ramle… - In Vitro Cellular & …, 2021 - Springer
The production of alkaloids in the intact plant is usually low, and some of them are tissue-
specific and growth stage–specific. In this study, the total alkaloid content (TAC) in Polyalthia …
specific and growth stage–specific. In this study, the total alkaloid content (TAC) in Polyalthia …
Local anaesthetic potential, metabolic profiling, molecular docking and in silico ADME studies of Ocimum forskolei, family Lamiaceae
EM Zahran, UR Abdelmohsen, MM Shalash… - Natural Product …, 2021 - Taylor & Francis
The present study aimed to detect the bioactive metabolites from Ocimum forskolei aerial
parts which are responsible for the local anaesthetic activity of the ethyl acetate fraction …
parts which are responsible for the local anaesthetic activity of the ethyl acetate fraction …
Bioactive Phytocompounds to fight against antimicrobial resistance
Antibiotics are the chemical substances secreted by microorganisms used for treating
several types of other microbial diseases. However, a repeated as well as regular use of the …
several types of other microbial diseases. However, a repeated as well as regular use of the …
Morinda lucida stem bark reversed the pattern and extent of lead nitrate-induced liver injury in Wistar rats
DO Adeyemi, AK Jolayemi, PO Awoniran - Morphologie, 2023 - Elsevier
Lead toxicity remains one of the most important occupational and environmental health
problems with characteristic features that are incompatible with life. Considering the …
problems with characteristic features that are incompatible with life. Considering the …
[HTML][HTML] Investigation of anaesthetic potentials of various extracts of Annona muricata (sour sop) in Wister albino rat and dog
AI Kisani, SA Saganuwan - Journal of King Saud University-Science, 2022 - Elsevier
Objectives Local and general anaesthetics currently used in clinical practice are not
absolutely safe and efficacious. Hence two or more drugs are used for induction and …
absolutely safe and efficacious. Hence two or more drugs are used for induction and …
Phosphate-Based Self-Immolative Linkers for the Delivery of Amine-Containing Drugs
M Đud, M Tichotová, E Procházková, O Baszczyňski - Molecules, 2021 - mdpi.com
Amine-containing drugs often show poor pharmacological properties, but these
disadvantages can be overcome by using a prodrug approach involving self-immolative …
disadvantages can be overcome by using a prodrug approach involving self-immolative …