Importance of the pig as a human biomedical model

JK Lunney, A Van Goor, KE Walker… - Science translational …, 2021 - science.org
Pigs have substantial potential as biomedical models for studying human developmental
processes, congenital diseases, and pathogen response mechanisms in addition to utility as …

A review of the pangenome: how it affects our understanding of genomic variation, selection and breeding in domestic animals?

Y Gong, Y Li, X Liu, Y Ma, L Jiang - Journal of Animal Science and …, 2023 - Springer
As large-scale genomic studies have progressed, it has been revealed that a single
reference genome pattern cannot represent genetic diversity at the species level. While …

Ensembl 2023

FJ Martin, MR Amode, A Aneja… - Nucleic acids …, 2023 - academic.oup.com
Abstract Ensembl (https://www. ensembl. org) has produced high-quality genomic resources
for vertebrates and model organisms for more than twenty years. During that time, our …

Ensembl 2020

AD Yates, P Achuthan, W Akanni, J Allen… - Nucleic acids …, 2020 - academic.oup.com
Abstract The Ensembl (https://www. ensembl. org) is a system for generating and distributing
genome annotation such as genes, variation, regulation and comparative genomics across …

[HTML][HTML] ABO genotype alters the gut microbiota by regulating GalNAc levels in pigs

H Yang, J Wu, X Huang, Y Zhou, Y Zhang, M Liu, Q Liu… - Nature, 2022 - nature.com
The composition of the intestinal microbiome varies considerably between individuals and is
correlated with health. Understanding the extent to which, and how, host genetics …

A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription

L Jin, Q Tang, S Hu, Z Chen, X Zhou, B Zeng… - Nature …, 2021 - nature.com
A comprehensive transcriptomic survey of pigs can provide a mechanistic understanding of
tissue specialization processes underlying economically valuable traits and accelerate their …

The European Variation Archive: a FAIR resource of genomic variation for all species

T Cezard, F Cunningham, SE Hunt… - Nucleic Acids …, 2022 - academic.oup.com
Abstract The European Variation Archive (EVA; https://www. ebi. ac. uk/eva/) is a resource
for sharing all types of genetic variation data (SNPs, indels, and structural variants) for all …

Long read genome assemblies complemented by single cell RNA-sequencing reveal genetic and cellular mechanisms underlying the adaptive evolution of yak

X Gao, S Wang, YF Wang, S Li, SX Wu, RG Yan… - Nature …, 2022 - nature.com
Wild yak (Bos mutus) and domestic yak (Bos grunniens) are adapted to high altitude
environment and have ecological, economic, and cultural significances on the Qinghai …

A cattle graph genome incorporating global breed diversity

A Talenti, J Powell, JD Hemmink, EAJ Cook… - Nature …, 2022 - nature.com
Despite only 8% of cattle being found in Europe, European breeds dominate current genetic
resources. This adversely impacts cattle research in other important global cattle breeds …

Trajectory of livestock genomics in South Asia: a comprehensive review

M Panigrahi, H Kumar, KA Saravanan, D Rajawat… - Gene, 2022 - Elsevier
Livestock plays a central role in sustaining human livelihood in South Asia. There are
numerous and distinct livestock species in South Asian countries. Several of them have …