Dihydrosphingosine driven enrichment of sphingolipids attenuates TGFβ induced collagen synthesis...

S Borodzicz-Jażdżyk, P Jażdżyk, W Łysik… - Frontiers in …, 2022 - frontiersin.org

Sphingolipids are a structural component of the cell membrane, derived from sphingosine,
an amino alcohol. Its sphingoid base undergoes various types of enzymatic transformations …

被引用次数：21 相关文章所有 4 个版本

Antifibrotic effect of AD-1 on lipopolysaccharide-mediated fibroblast injury in L929 cells and bleomycin-induced pulmonary fibrosis in mice

T Li, Y Chen, Y Li, G Chen, Y Zhao, G Su - Food & function, 2022 - pubs.rsc.org

20 (R)-25-methoxyl-dammarane-3β, 12β, 20-triol (25-OCH3–PPD, AD-1) is a dammarane
ginsenoside that is isolated from Panax notoginseng. The present study aimed to explore its …

被引用次数：4 相关文章所有 5 个版本

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Cytokine receptor-like factor 1 (CRLF1) promotes cardiac fibrosis via ERK1/2 signaling pathway

S Luo, Z Yang, R Chen, D You, F Teng, Y Yuan… - Journal of Zhejiang …, 2023 - Springer

Cardiac fibrosis is a cause of morbidity and mortality in people with heart disease. Anti-
fibrosis treatment is a significant therapy for heart disease, but there is still no thorough …

被引用次数：3 相关文章所有 5 个版本

细胞因子受体样因子1 (CRLF1) 通过ERK1/2 信号通路促进心脏纤维化

S LUO, Z YANG, R CHEN, D YOU, F TENG… - Journal of Zhejiang …, 2023 - jzus.zju.edu.cn

心脏纤维化是心脏疾病患者发病和死亡的原因之一. 抗纤维化治疗是一种治疗心脏疾病的重要
手段, 但目前对纤维化的机制仍缺乏深入了解. 本研究旨在确定细胞因子受体样因子1 (CRLF1) …

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[HTML][HTML] Recent highlights on the mechanistic basis of cardiovascular remodeling from the International Journal of Cardiology Heart & Vasculature

AC Fender, D Dobrev - International Journal of Cardiology. Heart & …, 2023 - ncbi.nlm.nih.gov

2 expression of classical pro-fibrotic mediators. These findings suggest ATF3 in
cardiomyocytes is essential for fibrosis formation, while ATF3 in myofibroblasts primarily …