Multidimensional processing in the amygdala

KM Gothard - Nature Reviews Neuroscience, 2020 - nature.com
Brain-wide circuits that coordinate affective and social behaviours intersect in the amygdala.
Consequently, amygdala lesions cause a heterogeneous array of social and non-social …

Lesion studies in contemporary neuroscience

AR Vaidya, MS Pujara, M Petrides, EA Murray… - Trends in cognitive …, 2019 - cell.com
Studies of humans with focal brain damage and non-human animals with experimentally
induced brain lesions have provided pivotal insights into the neural basis of behavior. As the …

Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques

M Mavigner, J Raper, Z Kovacs-Balint… - Science translational …, 2018 - science.org
The Zika virus (ZIKV) epidemic is associated with fetal brain lesions and other serious birth
defects classified as congenital ZIKV syndrome. Postnatal ZIKV infection in infants and …

Hippocampal volume and depression among young children

DM Barch, R Tillman, D Kelly, D Whalen… - Psychiatry Research …, 2019 - Elsevier
Clinical depression can occur in young children as early as age three. This very early onset
variant of depression shows the same clinical features with developmental adjustments as …

Recombinant SARS-CoV-2 Spike Protein and its Receptor Binding Domain stimulate release of different pro-inflammatory mediators via activation of distinct receptors …

I Tsilioni, TC Theoharides - Molecular Neurobiology, 2023 - Springer
SARS-CoV-2 infects cells via its spike (S) protein binding to its surface receptor angiotensin
converting enzyme 2 (ACE2) on target cells and results in acute symptoms involving …

Understanding the heterogeneity of anxiety using a translational neuroscience approach

CM Drzewiecki, AS Fox - Cognitive, Affective, & Behavioral Neuroscience, 2024 - Springer
Anxiety disorders affect millions of people worldwide and present a challenge in
neuroscience research because of their substantial heterogeneity in clinical presentation …

Advances in nonhuman primate models of autism: Integrating neuroscience and behavior

MD Bauman, CM Schumann - Experimental neurology, 2018 - Elsevier
Given the prevalence and societal impact of autism spectrum disorders (ASD), there is an
urgent need to develop innovative preventative strategies and treatments to reduce the …

Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques

J Raper, Z Kovacs-Balint, M Mavigner… - Nature …, 2020 - nature.com
Zika virus (ZIKV) infection has a profound impact on the fetal nervous system. The postnatal
period is also a time of rapid brain growth, and it is important to understand the potential …

IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin

I Tsilioni, AB Patel, H Pantazopoulos… - Proceedings of the …, 2019 - National Acad Sciences
Autism spectrum disorder (ASD) does not have a distinct pathogenesis or effective
treatment. Increasing evidence supports the presence of immune dysfunction and …

IL-38 inhibits microglial inflammatory mediators and is decreased in amygdala of children with autism spectrum disorder

I Tsilioni, H Pantazopoulos, P Conti… - Proceedings of the …, 2020 - National Acad Sciences
Autism spectrum disorder (ASD) is characterized by impaired social interactions and
communication. The pathogenesis of ASD is not known, but it involves activation of …