Sleep quality and aging: a systematic review on healthy older people, mild cognitive impairment and Alzheimer's disease
Aging is characterized by changes in the structure and quality of sleep. When the alterations
in sleep become substantial, they can generate or accelerate cognitive decline, even in the …
in sleep become substantial, they can generate or accelerate cognitive decline, even in the …
Sleep and its regulation: An emerging pathogenic and treatment frontier in Alzheimer's disease
A majority of patients with Alzheimer's disease (AD) experience some form of sleep
disruption, including nocturnal sleep fragmentation, increased daytime napping, decreased …
disruption, including nocturnal sleep fragmentation, increased daytime napping, decreased …
New and emerging approaches to better define sleep disruption and its consequences
Current approaches to quantify and diagnose sleep disorders and circadian rhythm
disruption are imprecise, laborious, and often do not relate well to key clinical and health …
disruption are imprecise, laborious, and often do not relate well to key clinical and health …
A novel electroencephalogram-derived measure of disrupted delta wave activity during sleep predicts all-cause mortality risk
Rationale: Conventional markers of sleep disturbance, based on manual
electroencephalography scoring, may not adequately capture important features of more …
electroencephalography scoring, may not adequately capture important features of more …
A novel EEG marker predicts perceived sleepiness and poor sleep quality
Abstract Study Objectives To determine if a novel EEG-derived continuous index of sleep
depth/alertness, the odds ratio product (ORP), predicts self-reported daytime sleepiness and …
depth/alertness, the odds ratio product (ORP), predicts self-reported daytime sleepiness and …
Sleep-based interventions in Alzheimer's disease: promising approaches from prevention to treatment along the disease trajectory
S Cordone, S Scarpelli, V Alfonsi, L De Gennaro… - Pharmaceuticals, 2021 - mdpi.com
The multifactorial nature of Alzheimer's disease (AD) has led scientific researchers to focus
on the modifiable and treatable risk factors of AD. Sleep fits into this context, given the …
on the modifiable and treatable risk factors of AD. Sleep fits into this context, given the …
[HTML][HTML] Sleep structure assessed by objective measurement in patients with mild cognitive impairment: A meta-analysis
J Wei, M Wang, Y Guo, Y Liu, X Dong - Sleep Medicine, 2024 - Elsevier
Objectives A meta-analysis was used to explore the characteristic changes in objective
sleep structure of patients with mild cognitive impairment (MCI) compared with cognitively …
sleep structure of patients with mild cognitive impairment (MCI) compared with cognitively …
The role of the sleep K‐complex on the conversion from mild cognitive impairment to Alzheimer's disease
M Gorgoni, J Cenani, S Scarpelli, A D'Atri… - Journal of Sleep …, 2024 - Wiley Online Library
The present literature points to an alteration of the human K‐complex during non‐rapid eye
movement sleep in Alzheimer's disease. Nevertheless, the few findings on the K‐complex …
movement sleep in Alzheimer's disease. Nevertheless, the few findings on the K‐complex …
Non-REM sleep electrophysiology in REM sleep behaviour disorder: A narrative mini-review
M Gorgoni, A Galbiati - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Abstract Isolated Rapid Eye Movement Sleep (REM) behaviour disorder (iRBD) is a
prodromal sign of neurodegenerative disorders. Empirical findings point to a role of non …
prodromal sign of neurodegenerative disorders. Empirical findings point to a role of non …
Sleep electroencephalography biomarkers of cognition in obstructive sleep apnea
Y Gu, JF Gagnon, M Kaminska - Journal of Sleep Research, 2023 - Wiley Online Library
Obstructive sleep apnea has been associated with cognitive impairment and may be linked
to disorders of cognitive function. These associations may be a result of intermittent …
to disorders of cognitive function. These associations may be a result of intermittent …