Sleep quality and aging: a systematic review on healthy older people, mild cognitive impairment and Alzheimer's disease

M Casagrande, G Forte, F Favieri, I Corbo - International journal of …, 2022 - mdpi.com
Aging is characterized by changes in the structure and quality of sleep. When the alterations
in sleep become substantial, they can generate or accelerate cognitive decline, even in the …

Sleep and its regulation: An emerging pathogenic and treatment frontier in Alzheimer's disease

BA Kent, HH Feldman, HB Nygaard - Progress in neurobiology, 2021 - Elsevier
A majority of patients with Alzheimer's disease (AD) experience some form of sleep
disruption, including nocturnal sleep fragmentation, increased daytime napping, decreased …

New and emerging approaches to better define sleep disruption and its consequences

B Lechat, H Scott, G Naik, K Hansen… - Frontiers in …, 2021 - frontiersin.org
Current approaches to quantify and diagnose sleep disorders and circadian rhythm
disruption are imprecise, laborious, and often do not relate well to key clinical and health …

A novel electroencephalogram-derived measure of disrupted delta wave activity during sleep predicts all-cause mortality risk

B Lechat, KL Hansen, YA Melaku, A Vakulin… - Annals of the …, 2022 - atsjournals.org
Rationale: Conventional markers of sleep disturbance, based on manual
electroencephalography scoring, may not adequately capture important features of more …

A novel EEG marker predicts perceived sleepiness and poor sleep quality

B Lechat, C Hirotsu, S Appleton, M Younes, RJ Adams… - Sleep, 2022 - academic.oup.com
Abstract Study Objectives To determine if a novel EEG-derived continuous index of sleep
depth/alertness, the odds ratio product (ORP), predicts self-reported daytime sleepiness and …

Sleep-based interventions in Alzheimer's disease: promising approaches from prevention to treatment along the disease trajectory

S Cordone, S Scarpelli, V Alfonsi, L De Gennaro… - Pharmaceuticals, 2021 - mdpi.com
The multifactorial nature of Alzheimer's disease (AD) has led scientific researchers to focus
on the modifiable and treatable risk factors of AD. Sleep fits into this context, given the …

[HTML][HTML] Sleep structure assessed by objective measurement in patients with mild cognitive impairment: A meta-analysis

J Wei, M Wang, Y Guo, Y Liu, X Dong - Sleep Medicine, 2024 - Elsevier
Objectives A meta-analysis was used to explore the characteristic changes in objective
sleep structure of patients with mild cognitive impairment (MCI) compared with cognitively …

The role of the sleep K‐complex on the conversion from mild cognitive impairment to Alzheimer's disease

M Gorgoni, J Cenani, S Scarpelli, A D'Atri… - Journal of Sleep …, 2024 - Wiley Online Library
The present literature points to an alteration of the human K‐complex during non‐rapid eye
movement sleep in Alzheimer's disease. Nevertheless, the few findings on the K‐complex …

Non-REM sleep electrophysiology in REM sleep behaviour disorder: A narrative mini-review

M Gorgoni, A Galbiati - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Abstract Isolated Rapid Eye Movement Sleep (REM) behaviour disorder (iRBD) is a
prodromal sign of neurodegenerative disorders. Empirical findings point to a role of non …

Sleep electroencephalography biomarkers of cognition in obstructive sleep apnea

Y Gu, JF Gagnon, M Kaminska - Journal of Sleep Research, 2023 - Wiley Online Library
Obstructive sleep apnea has been associated with cognitive impairment and may be linked
to disorders of cognitive function. These associations may be a result of intermittent …