The 2D microfluidics cookbook–modeling convection and diffusion in plane flow devices
A growing number of microfluidic systems operate not through networks of microchannels
but instead through using 2D flow fields. While the design rules for channel networks are …
but instead through using 2D flow fields. While the design rules for channel networks are …
Injection molded microfluidics for establishing high-density single cell arrays in an open hydrogel format
Here, we develop an injection molded microfluidic approach for single cell analysis by
making use of (1) rapidly curing injectable hydrogels,(2) a high density microfluidic weir trap …
making use of (1) rapidly curing injectable hydrogels,(2) a high density microfluidic weir trap …
Spatially selective cell treatment and collection for integrative drug testing using hydrodynamic flow focusing and shifting
Hydrodynamic focusing capable of readily producing and controlling laminar flow facilitates
drug treatment of cells in existing microfluidic culture devices. However, to expand …
drug treatment of cells in existing microfluidic culture devices. However, to expand …
Ferguson analysis of protein electromigration during single-cell electrophoresis in an open microfluidic device
In an open microfluidic device, we investigate protein polyacrylamide gel electrophoresis
(PAGE) separation performance on single-cell lysate. Single-cell protein electrophoresis is …
(PAGE) separation performance on single-cell lysate. Single-cell protein electrophoresis is …
“Chip-on-a-Transwell” Devices for User-Friendly Control of the Microenvironment of Cultured Cells
We present microfabricated poly (dimethylsiloxane) templates assembled atop Transwell
membranes (“Chip-on-a-Transwell”) for focal delivery of soluble reagents to cells. This …
membranes (“Chip-on-a-Transwell”) for focal delivery of soluble reagents to cells. This …
Real-time activation profiles of a single T cell arrays following controlled interaction with antigen-presenting cells
A Desalvo - 2019 - eprints.soton.ac.uk
The aim of this project was to develop a new microdevice to allow precise control of cellcell
interactions, and to apply it to measure T cell signalling in arrays of single cells in realtime …
interactions, and to apply it to measure T cell signalling in arrays of single cells in realtime …