Because of its similarity to humans in important respects, sheep (Ovis aries) are a common
animal model for translational research in cardiovascular surgery. However, some unique …

Tissue-engineered heart valves (TEHVs) are emerging alternatives to current valve
prostheses and prospectively a lifelong replacement. Calcification, a pathological …

Background—Living autologous vascular grafts with the capacity for regeneration and
growth may overcome the limitations of contemporary artificial prostheses. Particularly in …

Autologous fibrin-based tissue-engineered heart valves have demonstrated excellent
potential as patient-derived valve replacements. The present pilot study aims to evaluate the …

The tricuspid valve ensures unidirectional blood flow from the right atrium to the right
ventricle. The three tricuspid leaflets operate within a dynamic stress environment of shear …

There is an acute clinical need for small-calibre (< 6 mm) vascular grafts for surgery. The aim
of this study was to evaluate the long-term performance of a small-calibre graft produced …

Objective Decellularized extracellular matrix made from porcine small intestinal submucosa,
commercially available as CorMatrix (CorMatrix Cardiovascular, Inc, Roswell, Ga) is used off …

Aims: Heart valve tissue engineering aims to create a graft with improved durability
compared to routinely used valve substitutes. This study presents the function and …

This study features the longest experimental follow‐up for decellularized heart valves
implanted in an animal model. Porcine aortic heart valves were decellularized according to …

The creation of living heart valve replacements via tissue engineering is actively being
pursued by many research groups. Numerous strategies have been described, aimed either …