[HTML][HTML] Dengue virus infection–a review of pathogenesis, vaccines, diagnosis and therapy

BH Kok, HT Lim, CP Lim, NS Lai, CY Leow, CH Leow - Virus research, 2023 - Elsevier
The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

[HTML][HTML] Brolucizumab: evolution through preclinical and clinical studies and the implications for the management of neovascular age-related macular degeneration

QD Nguyen, A Das, DV Do, PU Dugel, A Gomes… - Ophthalmology, 2020 - Elsevier
Improving or maintaining visual acuity is the main goal for the treatment of neovascular age-
related macular degeneration (nAMD). Current nAMD standard of care dictates frequent …

Camelid single-domain antibodies: historical perspective and future outlook

M Arbabi-Ghahroudi - Frontiers in immunology, 2017 - frontiersin.org
Tremendous effort has been expended over the past two and a half decades to understand
many aspects of camelid heavy chain antibodies, from their biology, evolution, and …

Neovascular macular degeneration: a review of etiology, risk factors, and recent advances in research and therapy

A Pugazhendhi, M Hubbell, P Jairam… - International Journal of …, 2021 - mdpi.com
Neovascular age-related macular degeneration (exudative or wet AMD) is a prevalent,
progressive retinal degenerative macular disease that is characterized by …

A comprehensive comparison between camelid nanobodies and single chain variable fragments

Y Asaadi, FF Jouneghani, S Janani… - Biomarker Research, 2021 - Springer
By the emergence of recombinant DNA technology, many antibody fragments have been
developed devoid of undesired properties of natural immunoglobulins. Among them …

[图书][B] Parasitology: an integrated approach

A Gunn, SJ Pitt - 2022 - books.google.com
Parasitology Highly detailed textbook on parasites and parasite relationships The fully
revised edition of Parasitology: An Integrated Approach holds true to its engaging and easy …

Nanobody-based therapeutics against colorectal cancer: Precision therapies based on the personal mutanome profile and tumor neoantigens

A Moradi, MM Pourseif, B Jafari, S Parvizpour… - Pharmacological …, 2020 - Elsevier
Monoclonal antibodies and vaccines have widely been studied for the immunotherapy of
cancer, while their large size appears to limit their functionality in solid tumors, in large part …

A review of plant-based expression systems as a platform for single-domain recombinant antibody production

ADM Malaquias, LEC Marques, SS Pereira… - International Journal of …, 2021 - Elsevier
Monoclonal antibodies have contributed to improving the treatment of several diseases.
However, limitations related to pharmacokinetic parameters and production costs have …

Brolucizumab: a novel anti-VEGF humanized single-chain antibody fragment for treating w-AMD

L Ferro Desideri, CE Traverso… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Wet age-related macular degeneration (w-AMD) represents the leading cause
of visual impairment in the elderly in the developed countries. Intravitreal antivascular …