We present two standards developed by the Genomic Standards Consortium (GSC) for
reporting bacterial and archaeal genome sequences. Both are extensions of the Minimum …

This review commemorates the 40th anniversary of DNA sequencing, a period in which we
have already witnessed multiple technological revolutions and a growth in scale from a few …

Short read massive parallel sequencing has emerged as a standard diagnostic tool in the
medical setting. However, short read technologies have inherent limitations such as GC …

Genomes represent the starting point of genetic studies. Since the discovery of DNA
structure, scientists have devoted great efforts to determine their sequence in an exact way …

Since the completion of the human genome project in 2003, extraordinary progress has
been made in genome sequencing technologies, which has led to a decreased cost per …

Determining the order of nucleic acid residues in biological samples is an integral
component of a wide variety of research applications. Over the last fifty years large numbers …

The interaction between the human microbiome and immune system has an effect on
several human metabolic functions and impacts our well-being. Additionally, the interaction …

The human genome sequence has profoundly altered our understanding of biology, human
diversity, and disease. The path from the first draft sequence to our nascent era of personal …

The term next-generation sequencing is almost a decade old, but it remains the colloquial
way to describe highly parallel or high-output sequencing methods that produce data at or …

摘要高通量测序技术是DNA 测序发展历程的一个里程碑, 它为现代生命科学研究提供了
前所未有的机遇. 详细介绍了以454, Solexa 和SOLiD 为代表的第二代高通量测序技术 …