[HTML][HTML] Oxidative stress and mitochondrial dysfunction in early-onset and late-onset preeclampsia

R Marín, DI Chiarello, C Abad, D Rojas… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Preeclampsia is a pregnancy-specific syndrome with multisystem involvement which leads
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …

StAR protein and the regulation of steroid hormone biosynthesis

DM Stocco - Annual review of physiology, 2001 - annualreviews.org
▪ Abstract Steroid hormone biosynthesis is acutely regulated by pituitary trophic hormones
and other steroidogenic stimuli. This regulation requires the synthesis of a protein whose …

Transforming growth factor-β1 and diabetic nephropathy

AS Chang, CK Hathaway… - American Journal of …, 2016 - journals.physiology.org
Transforming growth factor-β1 (TGF-β1) is established to be involved in the pathogenesis of
diabetic nephropathy. The diabetic milieu enhances oxidative stress and induces the …

Mechanism of inflammatory associated impairment of sperm function, spermatogenesis and steroidogenesis

H Hasan, S Bhushan, M Fijak… - Frontiers in Endocrinology, 2022 - frontiersin.org
Infection and inflammation are relevant entities of male reproductive disorders that can lead
to sub-/infertility. Associated damage of the testis of affected men and in rodent models …

Testicular macrophage modulation of Leydig cell steroidogenesis

DB Hales - Journal of reproductive immunology, 2002 - Elsevier
This review will highlight recent advances in the study of the immuno-endocrinology of the
testis, in particular how macrophage-derived inflammatory mediators affect Leydig cell …

Transcriptional regulation of steroidogenic genes: STARD1, CYP11A1 and HSD3B

HA LaVoie, SR King - Experimental biology and medicine, 2009 - journals.sagepub.com
Expression of the genes that mediate the first steps in steroidogenesis, the steroidogenic
acute regulatory protein (STARD1), the cholesterol side-chain cleavage enzyme …

Gene expression profiling of human adrenocortical tumors using complementary deoxyribonucleic acid microarrays identifies several candidate genes as markers of …

F De Fraipont, M El Atifi, N Cherradi… - The Journal of …, 2005 - academic.oup.com
The aim of this study was to identify predictor sets of genes whose over-or underexpression
in human sporadic adrenocortical tumors would help to identify malignant vs. benign tumors …

Regulation of the steroidogenic acute regulatory protein expression: functional and physiological consequences

PR Manna, DM Stocco - Current Drug Targets-Immune …, 2005 - ingentaconnect.com
Steroid hormones are synthesized in steroidogenic cells of the adrenal, ovary, testis,
placenta and brain and are essential for normal reproductive function and bodily …

Therapeutic inhibitor of vascular smooth muscle cells

LL Kunz, JM Reno - US Patent 6,569,441, 2003 - Google Patents
2019-05-26 Assigned to CAPITAL ONE, NATIONAL ASSOCIATION, AS ADMINISTRATIVE
AGENT reassignment CAPITAL ONE, NATIONAL ASSOCIATION, AS ADMINISTRATIVE …

A brief history of the search for the protein (s) involved in the acute regulation of steroidogenesis

DM Stocco, AH Zhao, LN Tu, K Morohaku… - Molecular and Cellular …, 2017 - Elsevier
The synthesis of steroid hormones occurs in specific cells and tissues in the body in
response to trophic hormones and other signals. In order to synthesize steroids de novo …