The neurobiology of irritable bowel syndrome

EA Mayer, HJ Ryu, RR Bhatt - Molecular psychiatry, 2023 - nature.com
Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …

The progress of gut microbiome research related to brain disorders

S Zhu, Y Jiang, K Xu, M Cui, W Ye, G Zhao… - Journal of …, 2020 - Springer
There is increasing evidence showing that the dynamic changes in the gut microbiota can
alter brain physiology and behavior. Cognition was originally thought to be regulated only by …

DSM-5 criteria and depression severity: implications for clinical practice

JC Tolentino, SL Schmidt - Frontiers in psychiatry, 2018 - frontiersin.org
Background: Depression diagnosis requires five or more symptoms (Diagnostic and
Statistical Manual of Mental Disorders-DSM-5). One of them must be either Depressed mood …

Feeling down? A systematic review of the gut microbiota in anxiety/depression and irritable bowel syndrome

CA Simpson, A Mu, N Haslam, OS Schwartz… - Journal of affective …, 2020 - Elsevier
Background Anxiety/depression and irritable bowel syndrome (IBS) are highly prevalent and
burdensome conditions, whose co-occurrence is estimated between 44 and 84%. Shared …

The gut–brain axis in irritable bowel syndrome and inflammatory bowel disease

A Ancona, C Petito, I Iavarone, V Petito… - Digestive and Liver …, 2021 - Elsevier
Research increasingly demonstrates the bidirectional communication between gut
microbiota and the brain, enhancing the role of gut microbiota modulation in the treatment of …

Cumulative effect of psychological alterations on gastrointestinal symptom severity in irritable bowel syndrome

I Midenfjord, A Borg, H Törnblom… - Official journal of the …, 2021 - journals.lww.com
METHODS: Patients with IBS (Rome IV) completed validated questionnaires assessing GI
symptoms (Gastrointestinal Symptom Rating Scale, IBS version and IBS Severity Scoring …

Sleep quality and health related problems of shift work among resident physicians: a cross-sectional study

A Lahlouh, M Mustafa - Sleep medicine, 2020 - Elsevier
Objectives Shift work is defined as any irregular work schedule that extends beyond the
usual 9 am to 5 pm time frame. Evidence from outside medicine suggests that it may be …

Potential role of insulin on the pathogenesis of depression

XH Zou, LH Sun, W Yang, BJ Li, RJ Cui - Cell proliferation, 2020 - Wiley Online Library
The regulation of insulin on depression and depression‐like behaviour has been widely
reported. Insulin and activation of its receptor can promote learning and memory, affect the …

Is there a causal link between psychological disorders and functional gastrointestinal disorders?

N Koloski, G Holtmann, NJ Talley - Expert Review of …, 2020 - Taylor & Francis
Introduction Psychological distress is associated with functional gastrointestinal disorders
(FGIDs) including irritable bowel syndrome (IBS) and functional dyspepsia (FD) but only …

New Metabolic, Digestive, and Oxidative Stress‐Related Manifestations Associated with Posttraumatic Stress Disorder

BA Oroian, A Ciobica, D Timofte… - Oxidative Medicine …, 2021 - Wiley Online Library
Posttraumatic stress disorder (PTSD) represents a pressing and generally invalidating
syndrome that is triggered by a terrifying or stressful experience, relying on recurrently …