Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …

Antibiotics have transformed medicine, saving millions of lives since they were first used to
treat a bacterial infection. However, antibiotics administered to target a specific pathogen …

Acinetobacter baumannii and Klebsiella pneumoniae are opportunistic pathogens
frequently co-isolated from polymicrobial infections. The infections where these pathogens …

Biofilms are communities of bacteria forming high-density sessile colonies. Such a lifestyle
comes associated with costs and benefits: while the growth rate of biofilms is often lower …

Antibiotic resistance is currently one of the most important public health problems. The
golden age of antibiotic discovery ended decades ago, and new approaches are urgently …

Most bacteria in nature exist in aggregated communities known as biofilms, and cells within
a biofilm demonstrate major physiological changes compared to their planktonic …

Bacteria are single-celled organisms, but the survival of microbial communities relies on
complex dynamics at the molecular, cellular, and ecosystem scales. Antibiotic resistance, in …

Infections that involve interkingdom microbial communities, such as those between bacteria
and yeast pathogens, are difficult to treat, associated with worse patient outcomes, and may …

Interspecies interactions can drive the emergence of unexpected microbial phenotypes that
are not observed when studying monocultures. The cystic fibrosis (CF) lung consists of a …

Progressive obstructive lung disease secondary to chronic airway infection, coupled with
impaired host immunity, is the leading cause of morbidity and mortality in cystic fibrosis (CF) …