[HTML][HTML] A new era of neuro-oncology research pioneered by multi-omics analysis and machine learning
S Takahashi, M Takahashi, S Tanaka, S Takayanagi… - Biomolecules, 2021 - mdpi.com
Although the incidence of central nervous system (CNS) cancers is not high, it significantly
reduces a patient's quality of life and results in high mortality rates. A low incidence also …
reduces a patient's quality of life and results in high mortality rates. A low incidence also …
[HTML][HTML] Metabolomic and lipidomic profiling of gliomas—a new direction in personalized therapies
M Gaca-Tabaszewska, J Bogusiewicz, B Bojko - Cancers, 2022 - mdpi.com
Simple Summary Gliomas comprise an extremely diverse category of brain tumors that are
difficult to diagnose and treat. As a result, scientists continue to search for new treatment …
difficult to diagnose and treat. As a result, scientists continue to search for new treatment …
Semiconducting Cu x Ni 3− x (hexahydroxytriphenylene) 2 framework for electrochemical aptasensing of C6 glioma cells and epidermal growth factor receptor
C Guo, Z Li, F Duan, Z Zhang, F Marchetti… - Journal of Materials …, 2020 - pubs.rsc.org
A 2D CuNi metal–organic framework (MOF) named CuxNi3− x (HHTP) 2 was synthesized
with 2, 3, 6, 7, 10, 11-hexahydroxytriphenylene (HHTP) as the linker and was used as a …
with 2, 3, 6, 7, 10, 11-hexahydroxytriphenylene (HHTP) as the linker and was used as a …
[HTML][HTML] The mechanism of formononetin/calycosin compound optimizing the effects of temozolomide on C6 malignant glioma based on metabolomics and network …
S Li, J Li, Y Fan, T Huang, Y Zhou, H Fan… - Biomedicine & …, 2022 - Elsevier
The complex of formononetin and calycosin (FMN/CAL) shows a synergistic effect on
temozolomide in the treatment of malignant glioma, however the mechanism is unclear. We …
temozolomide in the treatment of malignant glioma, however the mechanism is unclear. We …
An adult Drosophila glioma model to highlight metabolic dysfunctions and evaluate the role of the serotonin 5‐HT7 receptor as a potential therapeutic target
M Bertrand, F Szeremeta, N Hervouet‐Coste… - The FASEB …, 2023 - Wiley Online Library
Gliomas account for 50% of brain cancers and are therefore the most common brain tumors.
Molecular alterations involved in adult gliomas have been identified and mainly affect …
Molecular alterations involved in adult gliomas have been identified and mainly affect …
Untangling the web of glioblastoma treatment resistance using a multi-omic and multidisciplinary approach
Glioblastoma (GBM), the most common human brain tumor, has been notoriously resistant to
treatment. As a result, the dismal overall survival of GBM patients has not changed over the …
treatment. As a result, the dismal overall survival of GBM patients has not changed over the …
[HTML][HTML] Metabolic Impact of Anticancer Drugs Pd2Spermine and Cisplatin on the Brain of Healthy Mice
TJ Carneiro, M Vojtek, S Gonçalves-Monteiro… - Pharmaceutics, 2022 - mdpi.com
The new palladium agent Pd2Spermine (Spm) has been reported to exhibit promising
cytotoxic properties, while potentially circumventing the known disadvantages associated to …
cytotoxic properties, while potentially circumventing the known disadvantages associated to …
A novel derivatization strategy for profiling phosphate ester/anhydride metabolic network and application on glioma rats using HILIC-MS/MS
N Sheng, H Zhao, X Chen, D Wang, M Li, Z Wang… - Talanta, 2021 - Elsevier
Phosphate esters and anhydrides have great significance in the field of biochemical
research and medical therapy. The genetic materials (DNA or RNA), most of the coenzymes …
research and medical therapy. The genetic materials (DNA or RNA), most of the coenzymes …
Integrative analysis of metabolomic and transcriptomic data reveals metabolic alterations in glioma patients
Y Shi, D Ding, L Liu, Z Li, L Zuo, L Zhou… - Journal of Proteome …, 2021 - ACS Publications
Glioma is a malignant brain tumor. There is growing evidence that its progression involves
altered metabolism. This study's objective was to understand how those metabolic …
altered metabolism. This study's objective was to understand how those metabolic …
Characterization of acidic glycosphingolipid changes in C6 glioma rats treated with temozolomide using ultra-high-performance liquid chromatography coupled with …
TK Ren, ML Li, H Zheng, Z Wang, JL Zhang - Journal of Analysis and …, 2020 - Springer
Ganglioside and sulfatide are primary components of acidic glycosphingolipids (AGSLs),
which are abundant in the brain tissue. AGSLs are potential tumor markers. In this paper, we …
which are abundant in the brain tissue. AGSLs are potential tumor markers. In this paper, we …