RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Conspectus The immune system has evolved over time to protect the host from foreign
microorganisms. Activation of the immune system is predicated on a distinction between self …

Despite the tremendous potential of peptide-based cancer vaccines, their efficacy has been
limited in humans. Recent innovations in tumour exome sequencing have signalled the new …

There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …

Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …

Although immune checkpoint blockade has shown initial success for various cancers, only a
small subset of patients benefits from this therapy. Some chemotherapeutic drugs have been …

Macrophages play a major role in the pathogenesis of atherosclerosis. Many studies have
shone light on the different phenotypes and functions that macrophages can acquire upon …

Phase‐change materials (PCMs) have emerged as a novel class of thermo‐responsive
materials for controlled release, where the payloads encapsulated in a solid matrix are …

The idea of employing natural cell membranes as a coating medium for nanoparticles (NPs)
endows man-made vectors with natural capabilities and benefits. In addition to retaining the …