Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

Adrenal venous sampling is recommended by current guidelines to identify surgically
curable causes of hyperaldosteronism but remains markedly underused. Key factors …

Primary aldosteronism (PA) is the most common form of secondary hypertension. In many
cases, somatic mutations in ion channels and pumps within adrenal cells initiate the …

In the 60 years that have passed since the discovery of the mineralocorticoid hormone
aldosterone, much has been learned about its synthesis (both adrenal and extra-adrenal) …

Primary aldosteronism (PA) is an endocrinopathy characterized by dysregulated
aldosterone production that occurs despite suppression of renin and angiotensin II, and that …

Primary aldosteronism (PA) is the most common cause of secondary hypertension and is
associated with increased morbidity and mortality when compared with blood pressure …

Context: In 22 patients with unilateral primary aldosteronism (UPA), unilateral laparoscopic
adrenalectomy (ADX) not only corrected hypokalemia and led to cure or improvement of …

Aldosterone hypersecretion in primary aldosteronism is unilateral (aldosterone producing
adenoma and primary unilateral hyperplasia) or bilateral (idiopathic adrenal hyperplasia) …

In patients with primary aldosteronism, adrenal vein sampling (AVS) is considered the only
reliable technique to distinguish between unilateral and bilateral autonomous production of …