Frailty is intertwined with heart failure: mechanisms, prevalence, prognosis, assessment, and management
Frailty, a syndrome characterized by an exaggerated decline in function and reserve of
multiple physiological systems, is common in older patients with heart failure (HF) and is …
multiple physiological systems, is common in older patients with heart failure (HF) and is …
Polypharmacy definition and prevalence in heart failure: a systematic review
J Beezer, M Al Hatrushi, A Husband, A Kurdi… - Heart failure …, 2022 - Springer
Polypharmacy and heart failure are becoming increasingly common due to an ageing
population and the rise of multimorbidity. Treating heart failure necessitates prescribing of …
population and the rise of multimorbidity. Treating heart failure necessitates prescribing of …
Prevalence and prognostic impact of the coexistence of multiple frailty domains in elderly patients with heart failure: the FRAGILE‐HF cohort study
Y Matsue, K Kamiya, H Saito, K Saito… - European journal of …, 2020 - Wiley Online Library
Aims To describe the prevalence, overlap, and prognostic implications of physical and social
frailties and cognitive dysfunction in hospitalized elderly patients with heart failure. Methods …
frailties and cognitive dysfunction in hospitalized elderly patients with heart failure. Methods …
Inflammatory pathways in heart failure with preserved left ventricular ejection fraction: implications for future interventions
NR Pugliese, P Pellicori, F Filidei… - Cardiovascular …, 2022 - academic.oup.com
Many patients with symptoms and signs of heart failure have a left ventricular ejection
fraction≥ 50%, termed heart failure with preserved ejection fraction (HFpEF). HFpEF is a …
fraction≥ 50%, termed heart failure with preserved ejection fraction (HFpEF). HFpEF is a …
Heart Failure Association of the European Society of Cardiology position paper on frailty in patients with heart failure
C Vitale, E Jankowska, L Hill, M Piepoli… - European journal of …, 2019 - Wiley Online Library
Heart failure (HF) and frailty are two distinct yet commonly associated conditions. The
interplay between the two conditions is complex, due to overlaps in underlying mechanisms …
interplay between the two conditions is complex, due to overlaps in underlying mechanisms …
Frailty status modifies the efficacy of exercise training among patients with chronic heart failure and reduced ejection fraction: an analysis from the HF-ACTION trial
Background: Supervised aerobic exercise training (ET) is recommended for stable
outpatients with heart failure (HF) with reduced ejection fraction (HFrEF). Frailty, a syndrome …
outpatients with heart failure (HF) with reduced ejection fraction (HFrEF). Frailty, a syndrome …
The prevalence and importance of frailty in heart failure with reduced ejection fraction–an analysis of PARADIGM‐HF and ATMOSPHERE
P Dewan, A Jackson, PS Jhund, L Shen… - European Journal of …, 2020 - Wiley Online Library
Aims Frailty, characterized by loss of homeostatic reserves and increased vulnerability to
physiological decompensation, results from an aggregation of insults across multiple organ …
physiological decompensation, results from an aggregation of insults across multiple organ …
Frailty, guideline-directed medical therapy, and outcomes in HFrEF: from the GUIDE-IT trial
Objectives In this study, we sought to evaluate the association of frailty with the use of
optimal guideline-directed medical therapy (GDMT) and outcomes in heart failure with …
optimal guideline-directed medical therapy (GDMT) and outcomes in heart failure with …
Identification of frailty and its risk factors in elderly hospitalized patients from different wards: a cross-sectional study in China
YD Liang, YN Zhang, YM Li, YH Chen… - … interventions in aging, 2019 - Taylor & Francis
Objectives To survey the difference of frailty prevalence in elderly inpatients amongdifferent
wards; to compare the diagnostic performance of five frailty measurements (Clinical Frailty …
wards; to compare the diagnostic performance of five frailty measurements (Clinical Frailty …
Frailty and the interactions between skeletal muscle, bone, and adipose tissue-impact on cardiovascular disease and possible therapeutic measures
ME Soto, I Pérez-Torres, ME Rubio-Ruiz… - International Journal of …, 2023 - mdpi.com
Frailty is a global health problem that impacts clinical practice. It is complex, having a
physical and a cognitive component, and it is the result of many contributing factors. Frail …
physical and a cognitive component, and it is the result of many contributing factors. Frail …